Cargando…

The synaptonemal complex central region modulates crossover pathways and feedback control of meiotic double-strand break formation

The synaptonemal complex (SC) is a proteinaceous structure that mediates homolog engagement and genetic recombination during meiosis. In budding yeast, Zip-Mer-Msh (ZMM) proteins promote crossover (CO) formation and initiate SC formation. During SC elongation, the SUMOylated SC component Ecm11 and t...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Min-Su, Higashide, Mika T, Choi, Hyungseok, Li, Ke, Hong, Soogil, Lee, Kangseok, Shinohara, Akira, Shinohara, Miki, Kim, Keun P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287913/
https://www.ncbi.nlm.nih.gov/pubmed/34197600
http://dx.doi.org/10.1093/nar/gkab566