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Endonuclease enrichment TAPS for cost-effective genome-wide base-resolution DNA methylation detection
Whole genome base-resolution methylome sequencing allows for the most comprehensive analysis of DNA methylation, however, the considerable sequencing cost often limits its applications. While reduced representation sequencing can be an affordable alternative, over 80% of CpGs in the genome are not c...
Autores principales: | Cheng, Jingfei, Siejka-Zielińska, Paulina, Liu, Yibin, Chandran, Anandhakumar, Kriaucionis, Skirmantas, Song, Chun-Xiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287915/ https://www.ncbi.nlm.nih.gov/pubmed/33905495 http://dx.doi.org/10.1093/nar/gkab291 |
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