Combinatorial analysis of translation dynamics reveals eIF2 dependence of translation initiation at near-cognate codons

Although ribosome-profiling and translation initiation sequencing (TI-seq) analyses have identified many noncanonical initiation codons, the precise detection of translation initiation sites (TISs) remains a challenge, mainly because of experimental artifacts of such analyses. Here, we describe a ne...

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Detalles Bibliográficos
Autores principales: Ichihara, Kazuya, Matsumoto, Akinobu, Nishida, Hiroshi, Kito, Yuki, Shimizu, Hideyuki, Shichino, Yuichi, Iwasaki, Shintaro, Imami, Koshi, Ishihama, Yasushi, Nakayama, Keiichi I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287933/
https://www.ncbi.nlm.nih.gov/pubmed/34226921
http://dx.doi.org/10.1093/nar/gkab549

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