Cargando…

Low Dose of Emodin Inhibits Hypercholesterolemia in a Rat Model of High Cholesterol

BACKGROUND: Emodin has been widely used in traditional Chinese medicine, but few studies have tried to understand the mechanism of its anti-hypercholesterolemic effect. MATERIAL/METHODS: To delineate the underlying pathways, high-cholesterol diet (HCD)-fed Sprague-Dawley rats were orally administrat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Jian-Hong, Lv, Chun-Fang, Guo, Xu-Jun, Zhang, Huan, Zhang, Jinde, Xu, Yangfeng, Wang, Jian, Liu, Sheng-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2021
Materias:	Animal Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287934/ https://www.ncbi.nlm.nih.gov/pubmed/34257265 http://dx.doi.org/10.12659/MSM.929346

Ejemplares similares

Emodin Attenuates Bleomycin-Induced Pulmonary Fibrosis via Anti-Inflammatory and Anti-Oxidative Activities in Rats
por: Tian, Sheng-Lan, et al.
Publicado: (2018)

Emodin Alleviates the Airway Inflammation of Cough Variant Asthma in Mice by Regulating the Notch Pathway
por: Hua, Shu, et al.
Publicado: (2019)

The Effects of Low-Dose and High-Dose Decoctions of Fructus aurantii in a Rat Model of Functional Dyspepsia
por: Zhu, Jing, et al.
Publicado: (2020)

Gypenosides Inhibits Xanthine Oxidoreductase and Ameliorates Urate Excretion in Hyperuricemic Rats Induced by High Cholesterol and High Fat Food (Lipid Emulsion)
por: Pang, Minxia, et al.
Publicado: (2017)

Early Protection by Resveratrol in Rat Lung Transplantation
por: Xu, Hai-Chao, et al.
Publicado: (2019)

Effects of an Enriched Extract of Paeoniflorin, a Monoterpene Glycoside used in Chinese Herbal Medicine, on Cholesterol Metabolism in a Hyperlipidemic Rat Model
por: Hu, Huiming, et al.
Publicado: (2017)

Effect of Iodine Intake on p14ARF and p16INK4a Expression in Thyroid Papillary Carcinoma in Rats
por: Sun, Ruimei, et al.
Publicado: (2015)

Intermedin 1-53 Inhibits Myocardial Fibrosis in Rats by Down-Regulating Transforming Growth Factor-β
por: Fang, Jian, et al.
Publicado: (2017)

Hypertonic Saline Alleviates Brain Edema After Traumatic Brain Injury via Downregulation of Aquaporin 4 in Rats
por: Yin, Jian, et al.
Publicado: (2018)

Effects of Aquaporin 4 Knockdown on Brain Edema of the Uninjured Side After Traumatic Brain Injury in Rats
por: Chen, Jian-Qiang, et al.
Publicado: (2016)

Pharmacodynamics of Five Anthraquinones (Aloe-emodin, Emodin, Rhein, Chysophanol, and Physcion) and Reciprocal Pharmacokinetic Interaction in Rats with Cerebral Ischemia
por: Li, Rong-Rong, et al.
Publicado: (2019)

Effect and Mechanism of QiShenYiQi Pill on Experimental Autoimmune Myocarditis Rats
por: Lv, Shichao, et al.
Publicado: (2016)

Apigenin Alleviates Myocardial Reperfusion Injury in Rats by Downregulating miR-15b
por: Wang, PeiPei, et al.
Publicado: (2019)

Neuroprotective Effect of Astragalus Polysacharin on Streptozotocin (STZ)-Induced Diabetic Rats
por: Zhang, Guyue, et al.
Publicado: (2019)

Interleukin-37 (IL-37) Suppresses Pertussis Toxin-Induced Inflammatory Myopathy in a Rat Model
por: Yan, Peng, et al.
Publicado: (2018)

MiR-206 Attenuates Denervation-Induced Skeletal Muscle Atrophy in Rats Through Regulation of Satellite Cell Differentiation via TGF-β1, Smad3, and HDAC4 Signaling
por: Huang, Qiang-Kai, et al.
Publicado: (2016)

Isobaric Tagging for Relative and Absolute Protein Quantification (iTRAQ)-Based Quantitative Proteomics Analysis of Differentially Expressed Proteins 1 Week After Spinal Cord Injury in a Rat Model
por: Liu, Shen, et al.
Publicado: (2020)

Gene Expression and Correlation of Pten and Fabp4 in Liver, Muscle, and Adipose Tissues of Type 2 Diabetes Rats
por: Su, Di, et al.
Publicado: (2015)

Substance P Inhibits the Collagen Synthesis of Rat Myocardial Fibroblasts Induced by Ang II
por: Yang, Zhiyong, et al.
Publicado: (2016)

Rotenone Attenuates Renal Injury in Aldosterone-Infused Rats by Inhibiting Oxidative Stress, Mitochondrial Dysfunction, and Inflammasome Activation
por: Ding, Wei, et al.
Publicado: (2015)

Protective Effects of Reduced Beta 2 Glycoprotein I on Liver Injury in Streptozotocin (STZ)-Diabetic Rats by Activation of AMP-Activated Protein Kinase
por: Zhang, Jing-Yun, et al.
Publicado: (2018)

A Novel Rat Model of Patellofemoral Osteoarthritis Due to Patella Baja, or Low-Lying Patella
por: Bei, Mingjian, et al.
Publicado: (2019)

Resveratrol Reduces Kidney Injury in a Rat Model of Uremia and is Associated with Increased Expression of Heat Shock Protein 70 (Hsp70)
por: Sun, Zhihong, et al.
Publicado: (2020)

Emodin and baicalein inhibit sodium taurocholate-induced vacuole formation in pancreatic acinar cells
por: Li, Jun, et al.
Publicado: (2018)

Effect of Naringin on Monosodium Iodoacetate-Induced Osteoarthritis Pain in Rats
por: Xu, Qiang, et al.
Publicado: (2017)

Protective Effect of Alendronate on Lumbar Facet Degeneration in Ovariectomized Rats
por: Zhang, Nan, et al.
Publicado: (2019)

Levetiracetam Protects Against Cognitive Impairment of Subthreshold Convulsant Discharge Model Rats by Activating Protein Kinase C (PKC)-Growth-Associated Protein 43 (GAP-43)-Calmodulin-Dependent Protein Kinase (CaMK) Signal Transduction Pathway
por: Wang, Min-Jian, et al.
Publicado: (2019)

Biochanin A Provides Neuroprotection Against Cerebral Ischemia/Reperfusion Injury by Nrf2-Mediated Inhibition of Oxidative Stress and Inflammation Signaling Pathway in Rats
por: Guo, Minmin, et al.
Publicado: (2019)

All-Trans Retinoic Acid Reduces Joint Adhesion Formation: An Experimental Study in Rats
por: Wang, Yuguang, et al.
Publicado: (2015)

Protective Effects of Hydrogen-Rich Water Against Cartilage Damage in a Rat Model of Osteoarthritis by Inhibiting Oxidative Stress, Matrix Catabolism, and Apoptosis
por: Cheng, ShaoWen, et al.
Publicado: (2020)

Esculetin Inhibits Proliferation, Invasion, and Migration of Laryngeal Cancer In Vitro and In Vivo by Inhibiting Janus Kinas (JAK)-Signal Transducer and Activator of Transcription-3 (STAT3) Activation
por: Zhang, Geng, et al.
Publicado: (2019)

Effects of Zinc Finger Protein A20 on Lipopolysaccharide (LPS)-Induced Pulmonary Inflammation/Anti-Inflammatory Mediators in an Acute Lung Injury/Acute Respiratory Distress Syndrome Rat Model
por: Wu, Ding-Qian, et al.
Publicado: (2017)

Upregulation of Chemokines in the Paraventricular Nucleus of the Hypothalamus in Rats with Stress-Induced Hypertension
por: Wu, Qin, et al.
Publicado: (2020)

The Role of the NOD1/Rip2 Signaling Pathway in Myocardial Remodeling in Spontaneously Hypertensive Rats
por: Liu, Feng-Yi, et al.
Publicado: (2020)

Pyrroloquinoline Quinone Inhibits Oxidative Stress in Rats with Diabetic Nephropathy
por: Zhang, Min, et al.
Publicado: (2020)

Effect of Urinary Kallidinogenase on Transforming Growth Factor-β(1) and High-Sensitivity C-Reactive Protein Expression in Rat Focal Cerebral Ischemic Injury
por: Dong, Ting-Fang, et al.
Publicado: (2016)

Myocardial Protective Effects of Nicorandil on Rats with Type 2 Diabetic Cardiomyopathy
por: Zhang, Meng, et al.
Publicado: (2018)

Ulinastatin Reduces the Severity of Intestinal Damage in the Neonatal Rat Model of Necrotizing Enterocolitis
por: Liang, Shuxia, et al.
Publicado: (2019)

Phosphorylated CaMKII levels increase in rat central nervous system after large-dose intravenous remifentanil
por: Wang, Qiang, et al.
Publicado: (2013)

Effects of Different Doses of Levetiracetam on Aquaporin 4 Expression in Rats with Brain Edema Following Fluid Percussion Injury
por: Jin, Hongbo, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_soo6520915iko1vojt392055iv