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5-Fluorouracil blocks quorum-sensing of biofilm-embedded methicillin-resistant Staphylococcus aureus in mice

Antibiotic-resistant pathogens often escape antimicrobial treatment by forming protective biofilms in response to quorum-sensing communication via diffusible autoinducers. Biofilm formation by the nosocomial pathogen methicillin-resistant Staphylococcus aureus (MRSA) is triggered by the quorum-senso...

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Detalles Bibliográficos
Autores principales: Sedlmayer, Ferdinand, Woischnig, Anne-Kathrin, Unterreiner, Vincent, Fuchs, Florian, Baeschlin, Daniel, Khanna, Nina, Fussenegger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287944/
https://www.ncbi.nlm.nih.gov/pubmed/33856484
http://dx.doi.org/10.1093/nar/gkab251