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5-Fluorouracil blocks quorum-sensing of biofilm-embedded methicillin-resistant Staphylococcus aureus in mice
Antibiotic-resistant pathogens often escape antimicrobial treatment by forming protective biofilms in response to quorum-sensing communication via diffusible autoinducers. Biofilm formation by the nosocomial pathogen methicillin-resistant Staphylococcus aureus (MRSA) is triggered by the quorum-senso...
Autores principales: | Sedlmayer, Ferdinand, Woischnig, Anne-Kathrin, Unterreiner, Vincent, Fuchs, Florian, Baeschlin, Daniel, Khanna, Nina, Fussenegger, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287944/ https://www.ncbi.nlm.nih.gov/pubmed/33856484 http://dx.doi.org/10.1093/nar/gkab251 |
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