Cargando…

iTARGEX analysis of yeast deletome reveals novel regulators of transcriptional buffering in S phase and protein turnover

Integrating omics data with quantification of biological traits provides unparalleled opportunities for discovery of genetic regulators by in silico inference. However, current approaches to analyze genetic-perturbation screens are limited by their reliance on annotation libraries for prioritization...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Jia-Hsin, Liao, You-Rou, Lin, Tzu-Chieh, Tsai, Cheng-Hung, Lai, Wei-Yun, Chou, Yang-Kai, Leu, Jun-Yi, Tsai, Huai-Kuang, Kao, Cheng-Fu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Computational Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287957/ https://www.ncbi.nlm.nih.gov/pubmed/34197604 http://dx.doi.org/10.1093/nar/gkab555

Ejemplares similares

Global Transcriptome and Deletome Profiles of Yeast Exposed to Transition Metals
por: Jin, Yong Hwan, et al.
Publicado: (2008)

Yeast Deletomics to Uncover Gadolinium Toxicity Targets and Resistance Mechanisms
por: Grosjean, Nicolas, et al.
Publicado: (2023)

Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae
por: Jo, William J, et al.
Publicado: (2009)

Global Deletome Profile of Saccharomyces cerevisiae Exposed to the Technology-Critical Element Yttrium
por: Grosjean, Nicolas, et al.
Publicado: (2018)

Identification and comparative analysis of long non-coding RNAs in the brain of fire ant queens in two different reproductive states
por: Tsai, Cheng-Hung, et al.
Publicado: (2022)

Differential Hsp90-dependent gene expression is strain-specific and common among yeast strains
por: Hung, Po-Hsiang, et al.
Publicado: (2023)

Experimental evolution reveals a general role for the methyltransferase Hmt1 in noise buffering
por: You, Shu-Ting, et al.
Publicado: (2019)

MYBS: a comprehensive web server for mining transcription factor binding sites in yeast
por: Tsai, Huai-Kuang, et al.
Publicado: (2007)

Evolution of cis-regulatory elements in yeast de novo and duplicated new genes
por: Tsai, Zing Tsung-Yeh, et al.
Publicado: (2012)

Borders of Cis-Regulatory DNA Sequences Preferentially Harbor the Divergent Transcription Factor Binding Motifs in the Human Genome
por: Huang, Jia-Hsin, et al.
Publicado: (2018)

Contribution of Sequence Motif, Chromatin State, and DNA Structure Features to Predictive Models of Transcription Factor Binding in Yeast
por: Tsai, Zing Tsung-Yeh, et al.
Publicado: (2015)

Impact of DNA-binding position variants on yeast gene expression
por: Swamy, Krishna B. S., et al.
Publicado: (2009)

Co-Expression of Neighboring Genes in the Zebrafish (Danio rerio) Genome
por: Tsai, Huai-Kuang, et al.
Publicado: (2009)

Carotid arterial mechanics as useful biomarker of extracellular matrix turnover and preserved ejection fraction heart failure
por: Zhou, Kevin Ning, et al.
Publicado: (2020)

Multiple Molecular Mechanisms Cause Reproductive Isolation between Three Yeast Species
por: Chou, Jui-Yu, et al.
Publicado: (2010)

Zebrafish, an In Vivo Platform to Screen Drugs and Proteins for Biomedical Use
por: Lee, Hung-Chieh, et al.
Publicado: (2021)

Breaches and buffers: Can meaningful work impact turnover during COVID-19 pandemic?
por: Heath, Michele L., et al.
Publicado: (2022)

H3K4 methylation at active genes mitigates transcription-replication conflicts during replication stress
por: Chong, Shin Yen, et al.
Publicado: (2020)

Genome-wide identification of associations between enhancer and alternative splicing in human and mouse
por: Shiau, Cheng-Kai, et al.
Publicado: (2022)

Mechanisms and therapeutic implications of RTA 408, an activator of Nrf2, in subarachnoid hemorrhage–induced delayed cerebral vasospasm and secondary brain injury
por: Tsai, Tai-Hsin, et al.
Publicado: (2020)

Evidence of association between Nucleosome Occupancy and the Evolution of Transcription Factor Binding Sites in Yeast
por: Swamy, Krishna BS, et al.
Publicado: (2011)

Comparative genomic analyses highlight the contribution of pseudogenized protein-coding genes to human lincRNAs
por: Liu, Wan-Hsin, et al.
Publicado: (2017)

A buffered media system for yeast batch culture growth
por: Prins, Rianne C., et al.
Publicado: (2021)

Co-expression of adjacent genes in yeast cannot be simply attributed to shared regulatory system
por: Tsai, Huai-Kuang, et al.
Publicado: (2007)

Work hours and turnover intention among hospital physicians in Taiwan: does income matter?
por: Tsai, Yu-Hsuan, et al.
Publicado: (2016)

TRIPBASE: a database for identifying the human genomic DNA and lncRNA triplexes
por: Lin, Tzu-Chieh, et al.
Publicado: (2023)

Effect of Buffers with Multiple Binding Sites on Calcium Waves
por: Kazmierczak, Bogdan, et al.
Publicado: (2022)

Primary ductal adenocarcinoma of lacrimal gland: Two case reports and review of the literature
por: Yang, Hsin-Yu, et al.
Publicado: (2018)

The prospective effects of workplace violence on physicians’ job satisfaction and turnover intentions: the buffering effect of job control
por: Heponiemi, Tarja, et al.
Publicado: (2014)

Fisheries portfolio diversification and turnover buffer Alaskan fishing communities from abrupt resource and market changes
por: Cline, Timothy J., et al.
Publicado: (2017)

Dosage compensation can buffer copy-number variation in wild yeast
por: Hose, James, et al.
Publicado: (2015)

The Efficacy of Transvaginal Ultrasound-Guided BoNT-A External Sphincter Injection in Female Patients with Underactive Bladder
por: Tsai, Cheng-Yen, et al.
Publicado: (2023)

Correction: Tsai et al. The Efficacy of Transvaginal Ultrasound-Guided BoNT-A External Sphincter Injection in Female Patients with Underactive Bladder. Toxins 2023, 15, 199
por: Tsai, Cheng-Yen, et al.
Publicado: (2023)

IsoPlot: a database for comparison of mRNA isoforms in fruit fly and mosquitoes
por: Ng, I-Man, et al.
Publicado: (2017)

Author Correction: Generation of convergent light beams by using surface plasmon locked Smith-Purcell radiation
por: Lai, Yi-Chieh, et al.
Publicado: (2017)

Generation of convergent light beams by using surface plasmon locked Smith-Purcell radiation
por: Lai, Yi-Chieh, et al.
Publicado: (2017)

Role of PVAT in obesity-related cardiovascular disease through the buffering activity of ATF3
por: Li, Hsiao-Fen, et al.
Publicado: (2022)

Zoledronate Inhibits Ischemia-Induced Neovascularization by Impairing the Mobilization and Function of Endothelial Progenitor Cells
por: Tsai, Shih-Hung, et al.
Publicado: (2012)

Constitutive turnover of histone H2A.Z at yeast promoters requires the preinitiation complex
por: Tramantano, Michael, et al.
Publicado: (2016)

The Yeast Nucleosome Atlas (YNA) database: an integrative gene mining platform for studying chromatin structure and its regulation in yeast
por: Hung, Po-Cheng, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_92p8igtvi8i521019iugvu2cg4