Argonaute integrated single-tube PCR system enables supersensitive detection of rare mutations

Technological advances in rare DNA mutations detection have revolutionized the diagnosis and monitoring of tumors, but they are still limited by the lack of supersensitive and high-coverage procedures for identifying low-abundance mutations. Here, we describe a single-tube, multiplex PCR-based syste...

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Detalles Bibliográficos
Autores principales: Liu, Qian, Guo, Xiang, Xun, Guanhua, Li, Zhonglei, Chong, Yuesheng, Yang, Litao, Wang, Hongxia, Zhang, Fengchun, Luo, Shukun, Cui, Li, Zhao, Pengshu, Ye, Xingyu, Xu, Heshan, Lu, Hui, Li, Xiao, Deng, Zixin, Li, Kai, Feng, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287959/
https://www.ncbi.nlm.nih.gov/pubmed/33905513
http://dx.doi.org/10.1093/nar/gkab274

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