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Comparison of multiple tractography methods for reconstruction of the retinogeniculate visual pathway using diffusion MRI
The retinogeniculate visual pathway (RGVP) conveys visual information from the retina to the lateral geniculate nucleus. The RGVP has four subdivisions, including two decussating and two nondecussating pathways that cannot be identified on conventional structural magnetic resonance imaging (MRI). Di...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288095/ https://www.ncbi.nlm.nih.gov/pubmed/33978265 http://dx.doi.org/10.1002/hbm.25472 |
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author | He, Jianzhong Zhang, Fan Xie, Guoqiang Yao, Shun Feng, Yuanjing Bastos, Dhiego C. A. Rathi, Yogesh Makris, Nikos Kikinis, Ron Golby, Alexandra J. O'Donnell, Lauren J. |
author_facet | He, Jianzhong Zhang, Fan Xie, Guoqiang Yao, Shun Feng, Yuanjing Bastos, Dhiego C. A. Rathi, Yogesh Makris, Nikos Kikinis, Ron Golby, Alexandra J. O'Donnell, Lauren J. |
author_sort | He, Jianzhong |
collection | PubMed |
description | The retinogeniculate visual pathway (RGVP) conveys visual information from the retina to the lateral geniculate nucleus. The RGVP has four subdivisions, including two decussating and two nondecussating pathways that cannot be identified on conventional structural magnetic resonance imaging (MRI). Diffusion MRI tractography has the potential to trace these subdivisions and is increasingly used to study the RGVP. However, it is not yet known which fiber tracking strategy is most suitable for RGVP reconstruction. In this study, four tractography methods are compared, including constrained spherical deconvolution (CSD) based probabilistic (iFOD1) and deterministic (SD‐Stream) methods, and multi‐fiber (UKF‐2T) and single‐fiber (UKF‐1T) unscented Kalman filter (UKF) methods. Experiments use diffusion MRI data from 57 subjects in the Human Connectome Project. The RGVP is identified using regions of interest created by two clinical experts. Quantitative anatomical measurements and expert anatomical judgment are used to assess the advantages and limitations of the four tractography methods. Overall, we conclude that UKF‐2T and iFOD1 produce the best RGVP reconstruction results. The iFOD1 method can better quantitatively estimate the percentage of decussating fibers, while the UKF‐2T method produces reconstructed RGVPs that are judged to better correspond to the known anatomy and have the highest spatial overlap across subjects. Overall, we find that it is challenging for current tractography methods to both accurately track RGVP fibers that correspond to known anatomy and produce an approximately correct percentage of decussating fibers. We suggest that future algorithm development for RGVP tractography should take consideration of both of these two points. |
format | Online Article Text |
id | pubmed-8288095 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley & Sons, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82880952021-07-21 Comparison of multiple tractography methods for reconstruction of the retinogeniculate visual pathway using diffusion MRI He, Jianzhong Zhang, Fan Xie, Guoqiang Yao, Shun Feng, Yuanjing Bastos, Dhiego C. A. Rathi, Yogesh Makris, Nikos Kikinis, Ron Golby, Alexandra J. O'Donnell, Lauren J. Hum Brain Mapp Research Articles The retinogeniculate visual pathway (RGVP) conveys visual information from the retina to the lateral geniculate nucleus. The RGVP has four subdivisions, including two decussating and two nondecussating pathways that cannot be identified on conventional structural magnetic resonance imaging (MRI). Diffusion MRI tractography has the potential to trace these subdivisions and is increasingly used to study the RGVP. However, it is not yet known which fiber tracking strategy is most suitable for RGVP reconstruction. In this study, four tractography methods are compared, including constrained spherical deconvolution (CSD) based probabilistic (iFOD1) and deterministic (SD‐Stream) methods, and multi‐fiber (UKF‐2T) and single‐fiber (UKF‐1T) unscented Kalman filter (UKF) methods. Experiments use diffusion MRI data from 57 subjects in the Human Connectome Project. The RGVP is identified using regions of interest created by two clinical experts. Quantitative anatomical measurements and expert anatomical judgment are used to assess the advantages and limitations of the four tractography methods. Overall, we conclude that UKF‐2T and iFOD1 produce the best RGVP reconstruction results. The iFOD1 method can better quantitatively estimate the percentage of decussating fibers, while the UKF‐2T method produces reconstructed RGVPs that are judged to better correspond to the known anatomy and have the highest spatial overlap across subjects. Overall, we find that it is challenging for current tractography methods to both accurately track RGVP fibers that correspond to known anatomy and produce an approximately correct percentage of decussating fibers. We suggest that future algorithm development for RGVP tractography should take consideration of both of these two points. John Wiley & Sons, Inc. 2021-05-12 /pmc/articles/PMC8288095/ /pubmed/33978265 http://dx.doi.org/10.1002/hbm.25472 Text en © 2021 The Authors. Human Brain Mapping published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Research Articles He, Jianzhong Zhang, Fan Xie, Guoqiang Yao, Shun Feng, Yuanjing Bastos, Dhiego C. A. Rathi, Yogesh Makris, Nikos Kikinis, Ron Golby, Alexandra J. O'Donnell, Lauren J. Comparison of multiple tractography methods for reconstruction of the retinogeniculate visual pathway using diffusion MRI |
title | Comparison of multiple tractography methods for reconstruction of the retinogeniculate visual pathway using diffusion MRI |
title_full | Comparison of multiple tractography methods for reconstruction of the retinogeniculate visual pathway using diffusion MRI |
title_fullStr | Comparison of multiple tractography methods for reconstruction of the retinogeniculate visual pathway using diffusion MRI |
title_full_unstemmed | Comparison of multiple tractography methods for reconstruction of the retinogeniculate visual pathway using diffusion MRI |
title_short | Comparison of multiple tractography methods for reconstruction of the retinogeniculate visual pathway using diffusion MRI |
title_sort | comparison of multiple tractography methods for reconstruction of the retinogeniculate visual pathway using diffusion mri |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288095/ https://www.ncbi.nlm.nih.gov/pubmed/33978265 http://dx.doi.org/10.1002/hbm.25472 |
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