When aggregation-induced emission meets protein aggregates

There is an unmet demand for research tools to monitor the multistep protein aggregation process in live cells, a process that has been associated with a growing number of human diseases. Recently, AIEgens have been developed to directly monitor the entire protein aggregation process in test tubes a...

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Detalles Bibliográficos
Autores principales: Tang, Sicheng, Ye, Songtao, Zhang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
CHEMISTRY
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288174/
https://www.ncbi.nlm.nih.gov/pubmed/34691668
http://dx.doi.org/10.1093/nsr/nwab013
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author Tang, Sicheng
Ye, Songtao
Zhang, Xin
author_facet Tang, Sicheng
Ye, Songtao
Zhang, Xin
author_sort Tang, Sicheng
collection PubMed
description There is an unmet demand for research tools to monitor the multistep protein aggregation process in live cells, a process that has been associated with a growing number of human diseases. Recently, AIEgens have been developed to directly monitor the entire protein aggregation process in test tubes and live cells. Future application of AIEgens is expected to shed light on both diagnosis and treatment of disease rooted in protein aggregation.
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spelling pubmed-82881742021-10-21 When aggregation-induced emission meets protein aggregates Tang, Sicheng Ye, Songtao Zhang, Xin Natl Sci Rev CHEMISTRY There is an unmet demand for research tools to monitor the multistep protein aggregation process in live cells, a process that has been associated with a growing number of human diseases. Recently, AIEgens have been developed to directly monitor the entire protein aggregation process in test tubes and live cells. Future application of AIEgens is expected to shed light on both diagnosis and treatment of disease rooted in protein aggregation. Oxford University Press 2021-01-25 /pmc/articles/PMC8288174/ /pubmed/34691668 http://dx.doi.org/10.1093/nsr/nwab013 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of China Science Publishing & Media Ltd. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle CHEMISTRY
Tang, Sicheng
Ye, Songtao
Zhang, Xin
When aggregation-induced emission meets protein aggregates
title When aggregation-induced emission meets protein aggregates
title_full When aggregation-induced emission meets protein aggregates
title_fullStr When aggregation-induced emission meets protein aggregates
title_full_unstemmed When aggregation-induced emission meets protein aggregates
title_short When aggregation-induced emission meets protein aggregates
title_sort when aggregation-induced emission meets protein aggregates
topic CHEMISTRY
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288174/
https://www.ncbi.nlm.nih.gov/pubmed/34691668
http://dx.doi.org/10.1093/nsr/nwab013
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