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R-group replacement database for medicinal chemistry
AIM: Generation of an R-group replacement system for compound optimization in medicinal chemistry. MATERIALS & METHODS: From bioactive compounds, analogue series (ASs) were systematically extracted and from these ASs, all R-groups were isolated and further analyzed. EXEMPLARY RESULTS & DATA:...
Autores principales: | Takeuchi, Kosuke, Kunimoto, Ryo, Bajorath, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Science Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288244/ https://www.ncbi.nlm.nih.gov/pubmed/34295541 http://dx.doi.org/10.2144/fsoa-2021-0062 |
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