De novo assembly of a Tibetan genome and identification of novel structural variants associated with high-altitude adaptation

Structural variants (SVs) may play important roles in human adaptation to extreme environments such as high altitude but have been under-investigated. Here, combining long-read sequencing with multiple scaffolding techniques, we assembled a high-quality Tibetan genome (ZF1), with a contig N50 length...

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Detalles Bibliográficos
Autores principales: He, Yaoxi, Lou, Haiyi, Cui, Chaoying, Deng, Lian, Gao, Yang, Zheng, Wangshan, Guo, Yongbo, Wang, Xiaoji, Ning, Zhilin, Li, Jun, Li, Bin, Bai, Caijuan, Liu, Shiming, Wu, Tianyi, Xu, Shuhua, Qi, Xuebin, Su, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288928/
https://www.ncbi.nlm.nih.gov/pubmed/34692055
http://dx.doi.org/10.1093/nsr/nwz160

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