Metabolic reprogramming in cancer: the bridge that connects intracellular stresses and cancer behaviors

Extensive changes in cellular metabolisms have been observed in cancer. They are probably induced by the same intracellular stressor, persistent off-balance in intracellular pH across possibly all adult cancers. It is these altered metabolisms that gives rise to a variety of cancerous behaviors such...

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Detalles Bibliográficos
Autores principales: Zhou, Yi, Sun, Huiyan, Xu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Biology & Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288940/
https://www.ncbi.nlm.nih.gov/pubmed/34692153
http://dx.doi.org/10.1093/nsr/nwaa082
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author Zhou, Yi
Sun, Huiyan
Xu, Ying
author_facet Zhou, Yi
Sun, Huiyan
Xu, Ying
author_sort Zhou, Yi
collection PubMed
description Extensive changes in cellular metabolisms have been observed in cancer. They are probably induced by the same intracellular stressor, persistent off-balance in intracellular pH across possibly all adult cancers. It is these altered metabolisms that gives rise to a variety of cancerous behaviors such as continuous cell division, metastasis and drug resistance.
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spelling pubmed-82889402021-10-21 Metabolic reprogramming in cancer: the bridge that connects intracellular stresses and cancer behaviors Zhou, Yi Sun, Huiyan Xu, Ying Natl Sci Rev Biology & Biochemistry Extensive changes in cellular metabolisms have been observed in cancer. They are probably induced by the same intracellular stressor, persistent off-balance in intracellular pH across possibly all adult cancers. It is these altered metabolisms that gives rise to a variety of cancerous behaviors such as continuous cell division, metastasis and drug resistance. Oxford University Press 2020-08 2020-04-30 /pmc/articles/PMC8288940/ /pubmed/34692153 http://dx.doi.org/10.1093/nsr/nwaa082 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of China Science Publishing & Media Ltd. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Biology & Biochemistry
Zhou, Yi
Sun, Huiyan
Xu, Ying
Metabolic reprogramming in cancer: the bridge that connects intracellular stresses and cancer behaviors
title Metabolic reprogramming in cancer: the bridge that connects intracellular stresses and cancer behaviors
title_full Metabolic reprogramming in cancer: the bridge that connects intracellular stresses and cancer behaviors
title_fullStr Metabolic reprogramming in cancer: the bridge that connects intracellular stresses and cancer behaviors
title_full_unstemmed Metabolic reprogramming in cancer: the bridge that connects intracellular stresses and cancer behaviors
title_short Metabolic reprogramming in cancer: the bridge that connects intracellular stresses and cancer behaviors
title_sort metabolic reprogramming in cancer: the bridge that connects intracellular stresses and cancer behaviors
topic Biology & Biochemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288940/
https://www.ncbi.nlm.nih.gov/pubmed/34692153
http://dx.doi.org/10.1093/nsr/nwaa082
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