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Complete Regression of Primary Cardiac Lymphoma With Dose-Attenuated R-CVP Chemotherapeutic Regimen

An elderly man was found to have a large right atrioventricular mass and pericardial effusion. He was diagnosed and treated as having primary cardiac lymphoma. A dose-attenuated chemotherapy regimen of rituximab, cyclophosphamide, vincristine, and prednisolone, with a cytoreductive pre-phase, afford...

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Autores principales: Mandal, Amit K.J., Selby, Faye L., Deoraj, Stuart, Metaxa, Sofia, Missouris, Constantinos G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289086/
https://www.ncbi.nlm.nih.gov/pubmed/34316819
http://dx.doi.org/10.1016/j.jaccas.2019.06.033
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author Mandal, Amit K.J.
Selby, Faye L.
Deoraj, Stuart
Metaxa, Sofia
Missouris, Constantinos G.
author_facet Mandal, Amit K.J.
Selby, Faye L.
Deoraj, Stuart
Metaxa, Sofia
Missouris, Constantinos G.
author_sort Mandal, Amit K.J.
collection PubMed
description An elderly man was found to have a large right atrioventricular mass and pericardial effusion. He was diagnosed and treated as having primary cardiac lymphoma. A dose-attenuated chemotherapy regimen of rituximab, cyclophosphamide, vincristine, and prednisolone, with a cytoreductive pre-phase, afforded complete regression of disease with resolution of the patient’s symptoms, and without deterioration in cardiac function or immunosuppression. The patient remains well 12 months after presentation. (Level of Difficulty: Advanced.)
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spelling pubmed-82890862021-07-26 Complete Regression of Primary Cardiac Lymphoma With Dose-Attenuated R-CVP Chemotherapeutic Regimen Mandal, Amit K.J. Selby, Faye L. Deoraj, Stuart Metaxa, Sofia Missouris, Constantinos G. JACC Case Rep Case Report An elderly man was found to have a large right atrioventricular mass and pericardial effusion. He was diagnosed and treated as having primary cardiac lymphoma. A dose-attenuated chemotherapy regimen of rituximab, cyclophosphamide, vincristine, and prednisolone, with a cytoreductive pre-phase, afforded complete regression of disease with resolution of the patient’s symptoms, and without deterioration in cardiac function or immunosuppression. The patient remains well 12 months after presentation. (Level of Difficulty: Advanced.) Elsevier 2019-09-04 /pmc/articles/PMC8289086/ /pubmed/34316819 http://dx.doi.org/10.1016/j.jaccas.2019.06.033 Text en © 2019 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Mandal, Amit K.J.
Selby, Faye L.
Deoraj, Stuart
Metaxa, Sofia
Missouris, Constantinos G.
Complete Regression of Primary Cardiac Lymphoma With Dose-Attenuated R-CVP Chemotherapeutic Regimen
title Complete Regression of Primary Cardiac Lymphoma With Dose-Attenuated R-CVP Chemotherapeutic Regimen
title_full Complete Regression of Primary Cardiac Lymphoma With Dose-Attenuated R-CVP Chemotherapeutic Regimen
title_fullStr Complete Regression of Primary Cardiac Lymphoma With Dose-Attenuated R-CVP Chemotherapeutic Regimen
title_full_unstemmed Complete Regression of Primary Cardiac Lymphoma With Dose-Attenuated R-CVP Chemotherapeutic Regimen
title_short Complete Regression of Primary Cardiac Lymphoma With Dose-Attenuated R-CVP Chemotherapeutic Regimen
title_sort complete regression of primary cardiac lymphoma with dose-attenuated r-cvp chemotherapeutic regimen
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289086/
https://www.ncbi.nlm.nih.gov/pubmed/34316819
http://dx.doi.org/10.1016/j.jaccas.2019.06.033
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