A Dramatic Response to Sirolimus Therapy in a Premature Infant With Massive Cardiac Rhabdomyoma

Cardiac rhabdomyomas in neonates may cause significant cardiac risk. Recently, sirolimus has been used to treat these lesions. The dose, duration, and monitoring for therapy are unknown. A case of sirolimus use in a premature neonate is presented. No significant adverse effects were seen. Review of...

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Detalles Bibliográficos
Autores principales: Lawley, Claire, Popat, Himanshu, Wong, Melanie, Badawi, Nadia, Ayer, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289154/
https://www.ncbi.nlm.nih.gov/pubmed/34316818
http://dx.doi.org/10.1016/j.jaccas.2019.07.030
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author Lawley, Claire
Popat, Himanshu
Wong, Melanie
Badawi, Nadia
Ayer, Julian
author_facet Lawley, Claire
Popat, Himanshu
Wong, Melanie
Badawi, Nadia
Ayer, Julian
author_sort Lawley, Claire
collection PubMed
description Cardiac rhabdomyomas in neonates may cause significant cardiac risk. Recently, sirolimus has been used to treat these lesions. The dose, duration, and monitoring for therapy are unknown. A case of sirolimus use in a premature neonate is presented. No significant adverse effects were seen. Review of published cases is included. (Level of Difficulty: Advanced.)
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spelling pubmed-82891542021-07-26 A Dramatic Response to Sirolimus Therapy in a Premature Infant With Massive Cardiac Rhabdomyoma Lawley, Claire Popat, Himanshu Wong, Melanie Badawi, Nadia Ayer, Julian JACC Case Rep Case Report Cardiac rhabdomyomas in neonates may cause significant cardiac risk. Recently, sirolimus has been used to treat these lesions. The dose, duration, and monitoring for therapy are unknown. A case of sirolimus use in a premature neonate is presented. No significant adverse effects were seen. Review of published cases is included. (Level of Difficulty: Advanced.) Elsevier 2019-10-16 /pmc/articles/PMC8289154/ /pubmed/34316818 http://dx.doi.org/10.1016/j.jaccas.2019.07.030 Text en Crown Copyright © 2019 Published by Elsevier on behalf of the American College of Cardiology Foundation. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Lawley, Claire
Popat, Himanshu
Wong, Melanie
Badawi, Nadia
Ayer, Julian
A Dramatic Response to Sirolimus Therapy in a Premature Infant With Massive Cardiac Rhabdomyoma
title A Dramatic Response to Sirolimus Therapy in a Premature Infant With Massive Cardiac Rhabdomyoma
title_full A Dramatic Response to Sirolimus Therapy in a Premature Infant With Massive Cardiac Rhabdomyoma
title_fullStr A Dramatic Response to Sirolimus Therapy in a Premature Infant With Massive Cardiac Rhabdomyoma
title_full_unstemmed A Dramatic Response to Sirolimus Therapy in a Premature Infant With Massive Cardiac Rhabdomyoma
title_short A Dramatic Response to Sirolimus Therapy in a Premature Infant With Massive Cardiac Rhabdomyoma
title_sort dramatic response to sirolimus therapy in a premature infant with massive cardiac rhabdomyoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289154/
https://www.ncbi.nlm.nih.gov/pubmed/34316818
http://dx.doi.org/10.1016/j.jaccas.2019.07.030
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