Simultaneous Formation of a Fully Organic Triply Dynamic Combinatorial Library

[Image: see text] Here we report the simultaneous formation of doubly and triply dynamic libraries as a result of exchange reactions between functionalized organic building blocks. A combination of three different reversible covalent linkages involving a boronate ester transesterification along with...

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Autores principales: Drożdż, Wojciech, Walczak, Anna, Stefankiewicz, Artur R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289287/
https://www.ncbi.nlm.nih.gov/pubmed/33904751
http://dx.doi.org/10.1021/acs.orglett.1c01042
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author Drożdż, Wojciech
Walczak, Anna
Stefankiewicz, Artur R.
author_facet Drożdż, Wojciech
Walczak, Anna
Stefankiewicz, Artur R.
author_sort Drożdż, Wojciech
collection PubMed
description [Image: see text] Here we report the simultaneous formation of doubly and triply dynamic libraries as a result of exchange reactions between functionalized organic building blocks. A combination of three different reversible covalent linkages involving a boronate ester transesterification along with an imine and disulfide exchange was employed to generate a new type of fully organic triply dynamic molecular assembly.
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spelling pubmed-82892872021-07-20 Simultaneous Formation of a Fully Organic Triply Dynamic Combinatorial Library Drożdż, Wojciech Walczak, Anna Stefankiewicz, Artur R. Org Lett [Image: see text] Here we report the simultaneous formation of doubly and triply dynamic libraries as a result of exchange reactions between functionalized organic building blocks. A combination of three different reversible covalent linkages involving a boronate ester transesterification along with an imine and disulfide exchange was employed to generate a new type of fully organic triply dynamic molecular assembly. American Chemical Society 2021-04-27 2021-05-07 /pmc/articles/PMC8289287/ /pubmed/33904751 http://dx.doi.org/10.1021/acs.orglett.1c01042 Text en © 2021 The Authors. Published byAmerican Chemical Society Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Drożdż, Wojciech
Walczak, Anna
Stefankiewicz, Artur R.
Simultaneous Formation of a Fully Organic Triply Dynamic Combinatorial Library
title Simultaneous Formation of a Fully Organic Triply Dynamic Combinatorial Library
title_full Simultaneous Formation of a Fully Organic Triply Dynamic Combinatorial Library
title_fullStr Simultaneous Formation of a Fully Organic Triply Dynamic Combinatorial Library
title_full_unstemmed Simultaneous Formation of a Fully Organic Triply Dynamic Combinatorial Library
title_short Simultaneous Formation of a Fully Organic Triply Dynamic Combinatorial Library
title_sort simultaneous formation of a fully organic triply dynamic combinatorial library
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289287/
https://www.ncbi.nlm.nih.gov/pubmed/33904751
http://dx.doi.org/10.1021/acs.orglett.1c01042
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AT walczakanna simultaneousformationofafullyorganictriplydynamiccombinatoriallibrary
AT stefankiewiczarturr simultaneousformationofafullyorganictriplydynamiccombinatoriallibrary

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