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Large-scale survey of prion protein genetic variability in scrapie disease-free goats from the United States

Scrapie is a slowly progressive neurodegenerative disease of small ruminants caused by an accumulation of an abnormal isoform of prion protein in the central nervous system. Polymorphisms of the prion protein gene (PRNP) strongly modulate scrapie resistance and incubation period in goats. The aim of...

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Detalles Bibliográficos
Autores principales: Zeineldin, Mohamed, Lehman, Kimberly, Urie, Natalie, Branan, Matthew, Wiedenheft, Alyson, Marshall, Katherine, Robbe-Austerman, Suelee, Thacker, Tyler
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289333/
https://www.ncbi.nlm.nih.gov/pubmed/34280230
http://dx.doi.org/10.1371/journal.pone.0254998