GeneReg: a constraint-based approach for design of feasible metabolic engineering strategies at the gene level

MOTIVATION: Large-scale metabolic models are widely used to design metabolic engineering strategies for diverse biotechnological applications. However, the existing computational approaches focus on alteration of reaction fluxes and often neglect the manipulations of gene expression to implement the...

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Detalles Bibliográficos
Autores principales: Razaghi-Moghadam, Zahra, Nikoloski, Zoran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289378/
https://www.ncbi.nlm.nih.gov/pubmed/33245091
http://dx.doi.org/10.1093/bioinformatics/btaa996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289378/
https://www.ncbi.nlm.nih.gov/pubmed/33245091
http://dx.doi.org/10.1093/bioinformatics/btaa996

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