Vortioxetine Improved Depressive State In Parkinson’s Disease

We report the case of a 67-year-old Japanese Parkinson’s disease (PD) patient with depression who was successfully treated with vortioxetine. The patient’s PD was being treated with levodopa (100 mg/day). As improvement was noted in PD symptoms, levodopa was continued. Subsequently, she was referred...

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Detalles Bibliográficos
Autores principales: Yoshimura, Reiji, Ikenouchi, Atsuko, Okamoto, Naomichi, Konishi, Yuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289392/
https://www.ncbi.nlm.nih.gov/pubmed/34290929
http://dx.doi.org/10.7759/cureus.15750
Descripción
Sumario:We report the case of a 67-year-old Japanese Parkinson’s disease (PD) patient with depression who was successfully treated with vortioxetine. The patient’s PD was being treated with levodopa (100 mg/day). As improvement was noted in PD symptoms, levodopa was continued. Subsequently, she was referred to our department due to worsening of her depressive symptoms, including depressed mood, anhedonia, decreased energy, decreased concentration, decreased motivation, insomnia, hopelessness, and worthlessness. The patient did not respond to paroxetine and escitalopram. Finally, vortioxetine improved her depressive state without worsening PD.

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