Vortioxetine Improved Depressive State In Parkinson’s Disease

We report the case of a 67-year-old Japanese Parkinson’s disease (PD) patient with depression who was successfully treated with vortioxetine. The patient’s PD was being treated with levodopa (100 mg/day). As improvement was noted in PD symptoms, levodopa was continued. Subsequently, she was referred...

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Detalles Bibliográficos
Autores principales: Yoshimura, Reiji, Ikenouchi, Atsuko, Okamoto, Naomichi, Konishi, Yuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289392/
https://www.ncbi.nlm.nih.gov/pubmed/34290929
http://dx.doi.org/10.7759/cureus.15750
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author Yoshimura, Reiji
Ikenouchi, Atsuko
Okamoto, Naomichi
Konishi, Yuki
author_facet Yoshimura, Reiji
Ikenouchi, Atsuko
Okamoto, Naomichi
Konishi, Yuki
author_sort Yoshimura, Reiji
collection PubMed
description We report the case of a 67-year-old Japanese Parkinson’s disease (PD) patient with depression who was successfully treated with vortioxetine. The patient’s PD was being treated with levodopa (100 mg/day). As improvement was noted in PD symptoms, levodopa was continued. Subsequently, she was referred to our department due to worsening of her depressive symptoms, including depressed mood, anhedonia, decreased energy, decreased concentration, decreased motivation, insomnia, hopelessness, and worthlessness. The patient did not respond to paroxetine and escitalopram. Finally, vortioxetine improved her depressive state without worsening PD.
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spelling pubmed-82893922021-07-20 Vortioxetine Improved Depressive State In Parkinson’s Disease Yoshimura, Reiji Ikenouchi, Atsuko Okamoto, Naomichi Konishi, Yuki Cureus Psychiatry We report the case of a 67-year-old Japanese Parkinson’s disease (PD) patient with depression who was successfully treated with vortioxetine. The patient’s PD was being treated with levodopa (100 mg/day). As improvement was noted in PD symptoms, levodopa was continued. Subsequently, she was referred to our department due to worsening of her depressive symptoms, including depressed mood, anhedonia, decreased energy, decreased concentration, decreased motivation, insomnia, hopelessness, and worthlessness. The patient did not respond to paroxetine and escitalopram. Finally, vortioxetine improved her depressive state without worsening PD. Cureus 2021-06-18 /pmc/articles/PMC8289392/ /pubmed/34290929 http://dx.doi.org/10.7759/cureus.15750 Text en Copyright © 2021, Yoshimura et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Psychiatry
Yoshimura, Reiji
Ikenouchi, Atsuko
Okamoto, Naomichi
Konishi, Yuki
Vortioxetine Improved Depressive State In Parkinson’s Disease
title Vortioxetine Improved Depressive State In Parkinson’s Disease
title_full Vortioxetine Improved Depressive State In Parkinson’s Disease
title_fullStr Vortioxetine Improved Depressive State In Parkinson’s Disease
title_full_unstemmed Vortioxetine Improved Depressive State In Parkinson’s Disease
title_short Vortioxetine Improved Depressive State In Parkinson’s Disease
title_sort vortioxetine improved depressive state in parkinson’s disease
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289392/
https://www.ncbi.nlm.nih.gov/pubmed/34290929
http://dx.doi.org/10.7759/cureus.15750
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AT ikenouchiatsuko vortioxetineimproveddepressivestateinparkinsonsdisease
AT okamotonaomichi vortioxetineimproveddepressivestateinparkinsonsdisease
AT konishiyuki vortioxetineimproveddepressivestateinparkinsonsdisease

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