Staphylococcus capitis Endocarditis of a Native Valve

Described as primarily an opportunistic pathogen, Staphylococcus capitis is primarily found as normal flora of the human skin but has been defined in literature as being a rare cause of infective endocarditis. We present a case of an otherwise healthy 65-year-old male who presented to our institution with symptoms similar to septic emboli. Blood cultures were obtained and ultimately grew Staphylococcus capitis in both bottles with repeat cultures one day later confirming the growth. A transthoracic echocardiogram was performed showing an ejection fraction of 60-65% and a thickened mitral value with mild-to-moderate mitral regurgitation. He was ultimately treated with IV cefazolin and improved with symptom resolution in outpatient follow-up. Staphylococcus capitis pathogenesis continues to be poorly understood, yet aggressive management with surgery and antibiotics has proven to decrease morbidity and mortality.