Healthcare workers acquired COVID-19 disease from patients? An investigation by phylogenomics

The increasing number of coronavirus disease 2019 (COVID-19) cases in the community has posed a significant epidemic pressure on healthcare settings. When healthcare workers (HCWs) acquire COVID-19, contact tracing and epidemiological investigation might not be adequate for determining the source of...

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Detalles Bibliográficos
Autores principales: Wong, R.C.W., Lee, M.K.P., Siu, G.K.H., Lee, L.K., Leung, J.S.L., Leung, E.C.M., Ho, Y.I.I., Lai, R.W.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Healthcare Infection Society. Published by Elsevier Ltd. 2021
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289439/
https://www.ncbi.nlm.nih.gov/pubmed/34098050
http://dx.doi.org/10.1016/j.jhin.2021.05.017
Descripción
Sumario:The increasing number of coronavirus disease 2019 (COVID-19) cases in the community has posed a significant epidemic pressure on healthcare settings. When healthcare workers (HCWs) acquire COVID-19, contact tracing and epidemiological investigation might not be adequate for determining the source of transmission. Here, we report a phylogenetic investigation involving two infected HCWs and nine patients to determine whether patient-to-HCW transmission had occurred in a hospital without a previous COVID-19 outbreak. This is the first study to apply phylogenomics to investigate suspected nosocomial transmission in a region with low prevalence of COVID-19. Our results do not support the occurrence of direct patient-to-HCW transmission.

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