CD16(+)CD163(+) monocytes traffic to sites of inflammation during necrotizing enterocolitis in premature infants

Necrotizing enterocolitis (NEC) is a severe gastrointestinal complication of prematurity. Using suspension and imaging mass cytometry coupled with single-cell RNA sequencing, we demonstrate severe inflammation in patients with NEC. NEC mucosa could be subtyped by an influx of three distinct neutroph...

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Detalles Bibliográficos
Autores principales: Olaloye, Oluwabunmi O., Liu, Peng, Toothaker, Jessica M., McCourt, Blake T., McCourt, Collin C., Xiao, Jenny, Prochaska, Erica, Shaffer, Spenser, Werner, Lael, Gringauz, Jordan, Good, Misty, Goldsmith, Jeffrey D., An, Xiaojing, Wang, Fujing, Snapper, Scott B., Shouval, Dror, Chen, Kong, Tseng, George, Konnikova, Liza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289692/
https://www.ncbi.nlm.nih.gov/pubmed/34269788
http://dx.doi.org/10.1084/jem.20200344

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