Cargando…
Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2
Heart injury has been reported in up to 20% of COVID-19 patients, yet the cause of myocardial histopathology remains unknown. Here, using an established in vivo hamster model, we demonstrate that SARS-CoV-2 can be detected in cardiomyocytes of infected animals. Furthermore, we found damaged cardiomy...
Autores principales: | Yang, Liuliu, Nilsson-Payant, Benjamin E., Han, Yuling, Jaffré, Fabrice, Zhu, Jiajun, Wang, Pengfei, Zhang, Tuo, Redmond, David, Houghton, Sean, Møller, Rasmus, Hoagland, Daisy, Carrau, Lucia, Horiuchi, Shu, Goff, Marisa, Lim, Jean K., Bram, Yaron, Richardson, Chanel, Chandar, Vasuretha, Borczuk, Alain, Huang, Yaoxing, Xiang, Jenny, Ho, David D., Schwartz, Robert E., tenOever, Benjamin R., Evans, Todd, Chen, Shuibing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289700/ https://www.ncbi.nlm.nih.gov/pubmed/34403650 http://dx.doi.org/10.1016/j.stemcr.2021.07.012 |
Ejemplares similares
-
Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2
por: Yang, Liuliu, et al.
Publicado: (2021) -
SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2
por: Chen, Shuibing, et al.
Publicado: (2020) -
SARS-CoV-2 Ion Channel ORF3a Enables TMEM16F-Dependent Phosphatidylserine Externalization to Augment Procoagulant Activity of the Tenase and Prothrombinase Complexes
por: Ludington, Jacob G, et al.
Publicado: (2021) -
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
por: Yang, Liuliu, et al.
Publicado: (2020) -
Dual-Reporter
System for Real-Time Monitoring of SARS-CoV-2
Main Protease Activity in Live Cells Enables Identification of
an Allosteric Inhibition Path
por: Bram, Yaron, et al.
Publicado: (2022)