Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2

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Heart injury has been reported in up to 20% of COVID-19 patients, yet the cause of myocardial histopathology remains unknown. Here, using an established in vivo hamster model, we demonstrate that SARS-CoV-2 can be detected in cardiomyocytes of infected animals. Furthermore, we found damaged cardiomy...

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Detalles Bibliográficos
Autores principales: Yang, Liuliu, Nilsson-Payant, Benjamin E., Han, Yuling, Jaffré, Fabrice, Zhu, Jiajun, Wang, Pengfei, Zhang, Tuo, Redmond, David, Houghton, Sean, Møller, Rasmus, Hoagland, Daisy, Carrau, Lucia, Horiuchi, Shu, Goff, Marisa, Lim, Jean K., Bram, Yaron, Richardson, Chanel, Chandar, Vasuretha, Borczuk, Alain, Huang, Yaoxing, Xiang, Jenny, Ho, David D., Schwartz, Robert E., tenOever, Benjamin R., Evans, Todd, Chen, Shuibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289700/
https://www.ncbi.nlm.nih.gov/pubmed/34403650
http://dx.doi.org/10.1016/j.stemcr.2021.07.012
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