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The REALISE score: a new statistically validated scoring system to assess the severity of anal fissures

BACKGROUND: Anal fissure (AF) is a common, painful disease that strongly affects patients’ quality of life, however, no scoring system to assess the severity of AF is available in the literature. The aim of this study was to set up and validate a reliable scoring system to quantify the severity of A...

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Autores principales: Picciariello, A., Lobascio, P., Spazzafumo, L., Rinaldi, M., Dibra, R., Trigiante, G., Laforgia, R., Pezzolla, A., Altomare, D. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289784/
https://www.ncbi.nlm.nih.gov/pubmed/33987779
http://dx.doi.org/10.1007/s10151-021-02459-y
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author Picciariello, A.
Lobascio, P.
Spazzafumo, L.
Rinaldi, M.
Dibra, R.
Trigiante, G.
Laforgia, R.
Pezzolla, A.
Altomare, D. F.
author_facet Picciariello, A.
Lobascio, P.
Spazzafumo, L.
Rinaldi, M.
Dibra, R.
Trigiante, G.
Laforgia, R.
Pezzolla, A.
Altomare, D. F.
author_sort Picciariello, A.
collection PubMed
description BACKGROUND: Anal fissure (AF) is a common, painful disease that strongly affects patients’ quality of life, however, no scoring system to assess the severity of AF is available in the literature. The aim of this study was to set up and validate a reliable scoring system to quantify the severity of AF, to be used in prospective trials comparing the efficacy and the outcomes of surgical or medical treatments. METHODS: The study was conducted on patients with acute or chronic AF and a control group in a tertiary centre for coloproctology in June 2020–September 2020. Two researchers independently carried out a structured interviewer-led questionnaire at two different time points (T1/T2). The questionnaire consisted of five items selected according to the most commonly reported symptoms for AF: the item pain, was scored from 0 to 10 using a visual analogue scale, and quality of life, duration of pain, use of painkillers, and bleeding were scored from 1 to 5 using Likert-scale questions. The scoRing systEm for AnaL fIsSurE (REALISE) score was the sum of the points. Patients with AF and a control group of patients with haemorrhoids, anal fistula, or obstructed defecation syndrome entered the study. Main outcome measures were reliability, inter-/intraobserver agreement, and repeatability. RESULTS: One hundred and fifty well-matched patients (75 with AF and 75 controls) were enrolled. A significant difference was found between the mean REALISE score for patients with AF and controls (p < 0.001). The two REALISE scores were highly correlated (r = 0.99). The coefficient of repeatability was 1.45 in T1 and 1.18 in T2. CONCLUSIONS: The REALISE score may have an important role in the assessment and management of AF, in grading the severity of AF and comparing results of different treatments.
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spelling pubmed-82897842021-08-05 The REALISE score: a new statistically validated scoring system to assess the severity of anal fissures Picciariello, A. Lobascio, P. Spazzafumo, L. Rinaldi, M. Dibra, R. Trigiante, G. Laforgia, R. Pezzolla, A. Altomare, D. F. Tech Coloproctol Original Article BACKGROUND: Anal fissure (AF) is a common, painful disease that strongly affects patients’ quality of life, however, no scoring system to assess the severity of AF is available in the literature. The aim of this study was to set up and validate a reliable scoring system to quantify the severity of AF, to be used in prospective trials comparing the efficacy and the outcomes of surgical or medical treatments. METHODS: The study was conducted on patients with acute or chronic AF and a control group in a tertiary centre for coloproctology in June 2020–September 2020. Two researchers independently carried out a structured interviewer-led questionnaire at two different time points (T1/T2). The questionnaire consisted of five items selected according to the most commonly reported symptoms for AF: the item pain, was scored from 0 to 10 using a visual analogue scale, and quality of life, duration of pain, use of painkillers, and bleeding were scored from 1 to 5 using Likert-scale questions. The scoRing systEm for AnaL fIsSurE (REALISE) score was the sum of the points. Patients with AF and a control group of patients with haemorrhoids, anal fistula, or obstructed defecation syndrome entered the study. Main outcome measures were reliability, inter-/intraobserver agreement, and repeatability. RESULTS: One hundred and fifty well-matched patients (75 with AF and 75 controls) were enrolled. A significant difference was found between the mean REALISE score for patients with AF and controls (p < 0.001). The two REALISE scores were highly correlated (r = 0.99). The coefficient of repeatability was 1.45 in T1 and 1.18 in T2. CONCLUSIONS: The REALISE score may have an important role in the assessment and management of AF, in grading the severity of AF and comparing results of different treatments. Springer International Publishing 2021-05-13 2021 /pmc/articles/PMC8289784/ /pubmed/33987779 http://dx.doi.org/10.1007/s10151-021-02459-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Picciariello, A.
Lobascio, P.
Spazzafumo, L.
Rinaldi, M.
Dibra, R.
Trigiante, G.
Laforgia, R.
Pezzolla, A.
Altomare, D. F.
The REALISE score: a new statistically validated scoring system to assess the severity of anal fissures
title The REALISE score: a new statistically validated scoring system to assess the severity of anal fissures
title_full The REALISE score: a new statistically validated scoring system to assess the severity of anal fissures
title_fullStr The REALISE score: a new statistically validated scoring system to assess the severity of anal fissures
title_full_unstemmed The REALISE score: a new statistically validated scoring system to assess the severity of anal fissures
title_short The REALISE score: a new statistically validated scoring system to assess the severity of anal fissures
title_sort realise score: a new statistically validated scoring system to assess the severity of anal fissures
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289784/
https://www.ncbi.nlm.nih.gov/pubmed/33987779
http://dx.doi.org/10.1007/s10151-021-02459-y
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