Cargando…

Endotrophin and C6Ma3, serological biomarkers of type VI collagen remodelling, reflect endoscopic and clinical disease activity in IBD

In inflammatory bowel disease (IBD), the chronic inflammation deeply affects the intestinal extracellular matrix. The aim of this study was to investigate if remodeling of the intestinal basement membrane type VI collagen was associated with pathophysiological changes in Crohn’s disease (CD) and ulc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lindholm, Majken, Godskesen, Line E., Manon-Jensen, Tina, Kjeldsen, Jens, Krag, Aleksander, Karsdal, Morten A., Mortensen, Joachim H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289827/ https://www.ncbi.nlm.nih.gov/pubmed/34282237 http://dx.doi.org/10.1038/s41598-021-94321-2

Ejemplares similares

Serum endotrophin, a type VI collagen cleavage product, is associated with increased mortality in chronic kidney disease
por: Fenton, Anthony, et al.
Publicado: (2017)

Endotrophin, a pro-peptide of Type VI collagen, is a biomarker of survival in cirrhotic patients with hepatocellular carcinoma
por: Leeming, Diana Julie, et al.
Publicado: (2020)

Endotrophin, a collagen type VI-derived matrikine, reflects the degree of renal fibrosis in patients with IgA nephropathy and in patients with ANCA-associated vasculitis
por: Sparding, Nadja, et al.
Publicado: (2021)

Inhibition of endotrophin, a cleavage product of collagen VI, confers cisplatin sensitivity to tumours
por: Park, Jiyoung, et al.
Publicado: (2013)

Circulating levels of endotrophin and cross-linked type III collagen reflect liver fibrosis in people with HIV
por: Dold, Leona, et al.
Publicado: (2023)

Endotrophin is associated with chronic multimorbidity and all-cause mortality in a cohort of elderly women
por: Staunstrup, Line Mærsk, et al.
Publicado: (2021)

The novel collagen matrikine, endotrophin, is associated with mortality and cardiovascular events in patients with atherosclerosis
por: Holm Nielsen, S., et al.
Publicado: (2021)

Ulcerative colitis, Crohn’s disease, and irritable bowel syndrome have different profiles of extracellular matrix turnover, which also reflects disease activity in Crohn’s disease
por: Mortensen, Joachim Høg, et al.
Publicado: (2017)

The Biological Role of the Collagen Alpha-3 (VI) Chain and Its Cleaved C5 Domain Fragment Endotrophin in Cancer
por: Wang, Jingya, et al.
Publicado: (2020)

Urinary endotrophin predicts disease progression in patients with chronic kidney disease
por: Rasmussen, Daniel Guldager Kring, et al.
Publicado: (2017)

Endotrophin, an extracellular hormone, in combination with neoepitope markers of von Willebrand factor improves prediction of mortality in the ECLIPSE COPD cohort
por: Rønnow, Sarah R., et al.
Publicado: (2020)

Endotrophin Levels Are Associated with Allograft Outcomes in Kidney Transplant Recipients
por: Sparding, Nadja, et al.
Publicado: (2023)

Serum type XVI collagen is associated with colorectal cancer and ulcerative colitis indicating a pathological role in gastrointestinal disorders
por: Jensen, Christina, et al.
Publicado: (2018)

Endotrophin, a fibroblast matrikine, may be a driver of fibroblast activation in fibro-inflammatory diseases
por: Reese-Petersen, Alexander L., et al.
Publicado: (2023)

Lack of evidence for a role of anthrax toxin receptors as surface receptors for collagen VI and for its cleaved-off C5 domain/endotrophin
por: Przyklenk, Matthias, et al.
Publicado: (2022)

The Mechanism for Adipose Endotrophin Production
por: Lee, Yun Sok
Publicado: (2022)

Endotrophin as a risk marker of mortality and kidney complications in a type 1 diabetes cohort
por: Møller, Alexandra Louise, et al.
Publicado: (2023)

Pretransplant endotrophin predicts delayed graft function after kidney transplantation
por: Tepel, Martin, et al.
Publicado: (2022)

Type VI collagen turnover-related peptides—novel serological biomarkers of muscle mass and anabolic response to loading in young men
por: Nedergaard, Anders, et al.
Publicado: (2013)

Combination Therapy of RAS Inhibition and SGLT2 Inhibitors Decreases Levels of Endotrophin in Persons with Type 2 Diabetes
por: Møller, Alexandra Louise, et al.
Publicado: (2023)

Plasma endotrophin, reflecting tissue fibrosis, is associated with graft failure and mortality in KTRs: results from two prospective cohort studies
por: Kremer, Daan, et al.
Publicado: (2022)

Endotrophin is a risk marker of complications in CANagliflozin cardioVascular Assessment Study (CANVAS): a randomized controlled trial
por: Rasmussen, Daniel Guldager Kring, et al.
Publicado: (2022)

Longitudinal serological assessment of type VI collagen turnover is related to progression in a real-world cohort of idiopathic pulmonary fibrosis
por: Jessen, Henrik, et al.
Publicado: (2021)

A serological type II collagen neoepitope biomarker reflects cartilage breakdown in patients with osteoarthritis
por: Groen, Solveig Skovlund, et al.
Publicado: (2021)

A Fragment of Collagen Type VI alpha-3 chain is Elevated in Serum from Patients with Gastrointestinal Disorders
por: Holm Nielsen, Signe, et al.
Publicado: (2020)

Endotrophin – Linking Obesity with Aggressive Tumor Growth
por: Park, Jiyoung, et al.
Publicado: (2012)

The impact of endotrophin on the progression of chronic liver disease
por: Kim, Min, et al.
Publicado: (2020)

Remote ischemic conditioning in active ulcerative colitis: An explorative randomized clinical trial
por: Godskesen, Line E., et al.
Publicado: (2020)

Matrix Metalloprotease Generated Fragments of Type VI Collagen Have Serum Biomarker Potential in Cancer – A Proof of Concept Study
por: Willumsen, Nicholas, et al.
Publicado: (2019)

Collagen Type III and VI Turnover in Response to Long-Term Immobilization
por: Sun, Shu, et al.
Publicado: (2015)

Inflammatory Biomarkers of Extracellular Matrix Remodeling and Disease Activity in Crohn’s Disease and Ulcerative Colitis
por: Domislovic, Viktor, et al.
Publicado: (2022)

Serological assessment of collagen fragments and tumor fibrosis may guide immune checkpoint inhibitor therapy
por: Jensen, Christina, et al.
Publicado: (2021)

Markers of Collagen Remodeling Detect Clinically Significant Fibrosis in Chronic Hepatitis C Patients
por: Nielsen, Mette J., et al.
Publicado: (2015)

The endothelial specific isoform of type XVIII collagen correlates to annual bleeding rate in haemophilia patients
por: Kjeld, Nadja Gad, et al.
Publicado: (2018)

Endotrophin: Nominated for best supporting actor in the fibro-inflammatory saga
por: Scherer, Philipp E., et al.
Publicado: (2021)

Collagen remodelling and plasma ascorbic acid levels in patients suspected of inherited bleeding disorders harbouring germline variants in collagen‐related genes
por: Fager Ferrari, Marcus, et al.
Publicado: (2020)

Type XXII Collagen Complements Fibrillar Collagens in the Serological Assessment of Tumor Fibrosis and the Outcome in Pancreatic Cancer
por: Madsen, Emilie A., et al.
Publicado: (2022)

Serological Biomarkers of Intestinal Collagen Turnover Identify Early Response to Infliximab Therapy in Patients With Crohn’s Disease
por: Alexdottir, Marta S., et al.
Publicado: (2022)

Serological Biomarkers of Tissue Turnover Identify Responders to Anti-TNF Therapy in Crohn's Disease: A Pilot Study
por: van Haaften, Wouter T., et al.
Publicado: (2020)

Progressive alcohol‐related liver fibrosis is characterised by imbalanced collagen formation and degradation
por: Thiele, Maja, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ftrb6qtfjopif89ubh1c6uua8g