Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway

Acquired heterotopic ossification (HO) is the extraskeletal bone formation after trauma. Various mesenchymal progenitors are reported to participate in ectopic bone formation. Here we induce acquired HO in mice by Achilles tenotomy and observe that conditional knockout (cKO) of fibroblast growth fac...

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Detalles Bibliográficos
Autores principales: Zhang, Dali, Huang, Junlan, Sun, Xianding, Chen, Hangang, Huang, Shuo, Yang, Jing, Du, Xiaolan, Tan, Qiaoyan, Luo, Fengtao, Zhang, Ruobin, Zhou, Siru, Jiang, Wanling, Ni, Zhenhong, Wang, Zuqiang, Jin, Min, Xu, Meng, Li, Fangfang, Chen, Liang, Liu, Mi, Su, Nan, Luo, Xiaoqing, Yin, Liangjun, Zhu, Ying, Feng, Jerry Q., Chen, Di, Qi, Huabing, Chen, Lin, Xie, Yangli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289847/
https://www.ncbi.nlm.nih.gov/pubmed/34282140
http://dx.doi.org/10.1038/s41467-021-24643-2

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