Cargando…
Incidental findings from cancer next generation sequencing panels
Next-generation sequencing (NGS) technologies have facilitated multi-gene panel (MGP) testing to detect germline DNA variants in hereditary cancer patients. This sensitive technique can uncover unexpected, non-germline incidental findings indicative of mosaicism, clonal hematopoiesis (CH), or hemato...
Autores principales: | Maani, Nika, Panabaker, Karen, McCuaig, Jeanna M., Buckley, Kathleen, Semotiuk, Kara, Farncombe, Kirsten M., Ainsworth, Peter, Panchal, Seema, Sadikovic, Bekim, Armel, Susan Randall, Lin, Hanxin, Kim, Raymond H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289933/ https://www.ncbi.nlm.nih.gov/pubmed/34282142 http://dx.doi.org/10.1038/s41525-021-00224-6 |
Ejemplares similares
-
Next-Generation Service Delivery: A Scoping Review of Patient Outcomes Associated with Alternative Models of Genetic Counseling and Genetic Testing for Hereditary Cancer
por: McCuaig, Jeanna M., et al.
Publicado: (2018) -
Analysis of Sequence and Copy Number Variants in Canadian Patient Cohort With Familial Cancer Syndromes Using a Unique Next Generation Sequencing Based Approach
por: Bhai, Pratibha, et al.
Publicado: (2021) -
A Comparison of Patient-Reported Outcomes Following Consent for Genetic Testing Using an Oncologist- or Genetic Counselor-Mediated Model of Care
por: McCuaig, Jeanna M., et al.
Publicado: (2021) -
NF1 Patients Receiving Breast Cancer Screening: Insights from The Ontario High Risk Breast Screening Program
por: Maani, Nika, et al.
Publicado: (2019) -
Genomic DNA Methylation-Derived Algorithm Enables Accurate Detection of Malignant Prostate Tissues
por: Aref-Eshghi, Erfan, et al.
Publicado: (2018)