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Ex vivo dendritic cell-based (DC) vaccine pulsed with a low dose of liposomal antigen and CpG-ODN improved PD-1 blockade immunotherapy
Lack of pre-existing tumor infiltrated T cells resulting in resistance to programmed cell death protein 1 (PD-1) blockade therapies can be solved by combining with anti-cancer vaccines and CpG-ODN in increasing T cell expansion and infiltration. Therefore, we prepared an ex vivo dendritic cell-based...
Autores principales: | Yazdani, Mona, Gholizadeh, Zahra, Nikpoor, Amin Reza, Mohamadian Roshan, Nema, Jaafari, Mahmoud Reza, Badiee, Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290007/ https://www.ncbi.nlm.nih.gov/pubmed/34282215 http://dx.doi.org/10.1038/s41598-021-94250-0 |
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