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Blood glutamate scavengers increase pro-apoptotic signaling and reduce metastatic melanoma growth in-vivo

Inhibition of extracellular glutamate (Glu) release decreases proliferation and invasion, induces apoptosis, and inhibits melanoma metastatic abilities. Previous studies have shown that Blood-glutamate scavenging (BGS), a novel treatment approach, has been found to be beneficial in attenuating gliob...

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Detalles Bibliográficos
Autores principales: Goldshmit, Yona, Perelroizen, Rita, Yakovchuk, Alex, Banyas, Evgeni, Mayo, Lior, David, Sari, Benbenishty, Amit, Blinder, Pablo, Shalom, Moshe, Ruban, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290021/
https://www.ncbi.nlm.nih.gov/pubmed/34282238
http://dx.doi.org/10.1038/s41598-021-94183-8