Fluoxetine increases brain MeCP2 immuno-positive cells in a female Mecp2 heterozygous mouse model of Rett syndrome through endogenous serotonin

Motor skill deficit is a common and invalidating symptom of Rett syndrome (RTT), a rare disease almost exclusively affecting girls during the first/second year of life. Loss-of-function mutations of the methyl-CpG-binding protein2 (MECP2; Mecp2 in rodents) gene is the cause in most patients. We rece...

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Detalles Bibliográficos
Autores principales: Villani, Claudia, Carli, Mirjana, Castaldo, Anna Maria, Sacchetti, Giuseppina, Invernizzi, Roberto William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290043/
https://www.ncbi.nlm.nih.gov/pubmed/34282222
http://dx.doi.org/10.1038/s41598-021-94156-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290043/
https://www.ncbi.nlm.nih.gov/pubmed/34282222
http://dx.doi.org/10.1038/s41598-021-94156-x

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