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Fluoxetine increases brain MeCP2 immuno-positive cells in a female Mecp2 heterozygous mouse model of Rett syndrome through endogenous serotonin
Motor skill deficit is a common and invalidating symptom of Rett syndrome (RTT), a rare disease almost exclusively affecting girls during the first/second year of life. Loss-of-function mutations of the methyl-CpG-binding protein2 (MECP2; Mecp2 in rodents) gene is the cause in most patients. We rece...
Autores principales: | Villani, Claudia, Carli, Mirjana, Castaldo, Anna Maria, Sacchetti, Giuseppina, Invernizzi, Roberto William |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290043/ https://www.ncbi.nlm.nih.gov/pubmed/34282222 http://dx.doi.org/10.1038/s41598-021-94156-x |
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