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Metabolic Seizures

Metabolic diseases should always be considered when evaluating children presenting with seizures. This is because many metabolic disorders are potentially treatable and seizure control can be achieved when these diseases are appropriately treated. Seizures caused by underlying metabolic diseases (me...

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Autores principales: Almannai, Mohammed, Al Mahmoud, Rabah A., Mekki, Mohammed, El-Hattab, Ayman W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290068/
https://www.ncbi.nlm.nih.gov/pubmed/34295297
http://dx.doi.org/10.3389/fneur.2021.640371
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author Almannai, Mohammed
Al Mahmoud, Rabah A.
Mekki, Mohammed
El-Hattab, Ayman W.
author_facet Almannai, Mohammed
Al Mahmoud, Rabah A.
Mekki, Mohammed
El-Hattab, Ayman W.
author_sort Almannai, Mohammed
collection PubMed
description Metabolic diseases should always be considered when evaluating children presenting with seizures. This is because many metabolic disorders are potentially treatable and seizure control can be achieved when these diseases are appropriately treated. Seizures caused by underlying metabolic diseases (metabolic seizures) should be particularly considered in unexplained neonatal seizures, refractory seizures, seizures related to fasting or food intake, seizures associated with other systemic or neurologic features, parental consanguinity, and family history of epilepsy. Metabolic seizures can be caused by various amino acids metabolic disorders, disorders of energy metabolism, cofactor-related metabolic diseases, purine and pyrimidine metabolic diseases, congenital disorders of glycosylation, and lysosomal and peroxisomal disorders. Diagnosing metabolic seizures without delay is essential because the immediate initiation of appropriate therapy for many metabolic diseases can prevent or minimize complications.
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spelling pubmed-82900682021-07-21 Metabolic Seizures Almannai, Mohammed Al Mahmoud, Rabah A. Mekki, Mohammed El-Hattab, Ayman W. Front Neurol Neurology Metabolic diseases should always be considered when evaluating children presenting with seizures. This is because many metabolic disorders are potentially treatable and seizure control can be achieved when these diseases are appropriately treated. Seizures caused by underlying metabolic diseases (metabolic seizures) should be particularly considered in unexplained neonatal seizures, refractory seizures, seizures related to fasting or food intake, seizures associated with other systemic or neurologic features, parental consanguinity, and family history of epilepsy. Metabolic seizures can be caused by various amino acids metabolic disorders, disorders of energy metabolism, cofactor-related metabolic diseases, purine and pyrimidine metabolic diseases, congenital disorders of glycosylation, and lysosomal and peroxisomal disorders. Diagnosing metabolic seizures without delay is essential because the immediate initiation of appropriate therapy for many metabolic diseases can prevent or minimize complications. Frontiers Media S.A. 2021-07-06 /pmc/articles/PMC8290068/ /pubmed/34295297 http://dx.doi.org/10.3389/fneur.2021.640371 Text en Copyright © 2021 Almannai, Al Mahmoud, Mekki and El-Hattab. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Almannai, Mohammed
Al Mahmoud, Rabah A.
Mekki, Mohammed
El-Hattab, Ayman W.
Metabolic Seizures
title Metabolic Seizures
title_full Metabolic Seizures
title_fullStr Metabolic Seizures
title_full_unstemmed Metabolic Seizures
title_short Metabolic Seizures
title_sort metabolic seizures
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290068/
https://www.ncbi.nlm.nih.gov/pubmed/34295297
http://dx.doi.org/10.3389/fneur.2021.640371
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