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Characteristics and outcomes of family-practice patients with coronavirus disease 2019: a case series

BACKGROUND: The clinical history and outcomes of coronavirus disease 2019 among people not hospitalized is not yet well characterized. To better inform clinical evaluation, we set out to characterize the natural history of coronavirus disease 2019 in primary health care. METHODS: Case series of all...

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Autores principales: Dzieciolowska, Stefania, Ravi, Oumeet, Grad, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290383/
https://www.ncbi.nlm.nih.gov/pubmed/34284815
http://dx.doi.org/10.1186/s13256-021-02963-7
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author Dzieciolowska, Stefania
Ravi, Oumeet
Grad, Roland
author_facet Dzieciolowska, Stefania
Ravi, Oumeet
Grad, Roland
author_sort Dzieciolowska, Stefania
collection PubMed
description BACKGROUND: The clinical history and outcomes of coronavirus disease 2019 among people not hospitalized is not yet well characterized. To better inform clinical evaluation, we set out to characterize the natural history of coronavirus disease 2019 in primary health care. METHODS: Case series of all patients rostered to physicians at a university-affiliated Family Medicine clinic. Cases met the Centers for Disease Control and Prevention definition of coronavirus disease 2019 from March 1 to May 21 2020. RESULTS: In total, 89 patients meeting Centers for Disease Control and Prevention criteria for coronavirus disease 2019 were documented. Their average age was 55.6 years (range 6–95 years), and all but one was symptomatic. Fifty-seven cases (64%) had a polymerase chain reaction test for coronavirus disease 2019, of whom 77.2% tested positive. Thirty cases (33.7%) reported contact with a confirmed or probable case of coronavirus disease 2019. Based on the Charlson Comorbidity Index, 28 cases (31.5%) had no comorbid conditions. The median number of days from symptom onset to first polymerase chain reaction test was 6 days (interquartile range 2.3–11 days). The median duration of fever was 3.5 days (interquartile range 1–7 days). Twenty-four cases (27%) visited the Emergency Department, and 10 were admitted to hospital. The median number of days between symptom onset and first Emergency Department visit was 8 days (interquartile range 3.5–27 days). CONCLUSIONS: At the start of this pandemic, the implementation of basic measures such as diagnostic testing was delayed. If we are to improve our control over the spread of coronavirus disease 2019, we will need to substantially reduce the time from symptom onset to diagnostic testing, and subsequent contact tracing. To minimize unnecessary Emergency Department visits, we propose a testable strategy for Family Medicine to engage with coronavirus disease 2019 patients in the acute phase of their illness. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13256-021-02963-7.
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spelling pubmed-82903832021-07-20 Characteristics and outcomes of family-practice patients with coronavirus disease 2019: a case series Dzieciolowska, Stefania Ravi, Oumeet Grad, Roland J Med Case Rep Research Article BACKGROUND: The clinical history and outcomes of coronavirus disease 2019 among people not hospitalized is not yet well characterized. To better inform clinical evaluation, we set out to characterize the natural history of coronavirus disease 2019 in primary health care. METHODS: Case series of all patients rostered to physicians at a university-affiliated Family Medicine clinic. Cases met the Centers for Disease Control and Prevention definition of coronavirus disease 2019 from March 1 to May 21 2020. RESULTS: In total, 89 patients meeting Centers for Disease Control and Prevention criteria for coronavirus disease 2019 were documented. Their average age was 55.6 years (range 6–95 years), and all but one was symptomatic. Fifty-seven cases (64%) had a polymerase chain reaction test for coronavirus disease 2019, of whom 77.2% tested positive. Thirty cases (33.7%) reported contact with a confirmed or probable case of coronavirus disease 2019. Based on the Charlson Comorbidity Index, 28 cases (31.5%) had no comorbid conditions. The median number of days from symptom onset to first polymerase chain reaction test was 6 days (interquartile range 2.3–11 days). The median duration of fever was 3.5 days (interquartile range 1–7 days). Twenty-four cases (27%) visited the Emergency Department, and 10 were admitted to hospital. The median number of days between symptom onset and first Emergency Department visit was 8 days (interquartile range 3.5–27 days). CONCLUSIONS: At the start of this pandemic, the implementation of basic measures such as diagnostic testing was delayed. If we are to improve our control over the spread of coronavirus disease 2019, we will need to substantially reduce the time from symptom onset to diagnostic testing, and subsequent contact tracing. To minimize unnecessary Emergency Department visits, we propose a testable strategy for Family Medicine to engage with coronavirus disease 2019 patients in the acute phase of their illness. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13256-021-02963-7. BioMed Central 2021-07-20 /pmc/articles/PMC8290383/ /pubmed/34284815 http://dx.doi.org/10.1186/s13256-021-02963-7 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Dzieciolowska, Stefania
Ravi, Oumeet
Grad, Roland
Characteristics and outcomes of family-practice patients with coronavirus disease 2019: a case series
title Characteristics and outcomes of family-practice patients with coronavirus disease 2019: a case series
title_full Characteristics and outcomes of family-practice patients with coronavirus disease 2019: a case series
title_fullStr Characteristics and outcomes of family-practice patients with coronavirus disease 2019: a case series
title_full_unstemmed Characteristics and outcomes of family-practice patients with coronavirus disease 2019: a case series
title_short Characteristics and outcomes of family-practice patients with coronavirus disease 2019: a case series
title_sort characteristics and outcomes of family-practice patients with coronavirus disease 2019: a case series
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290383/
https://www.ncbi.nlm.nih.gov/pubmed/34284815
http://dx.doi.org/10.1186/s13256-021-02963-7
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