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A Romanian study on the impact of glypressin in laparoscopic myomectomy
A major myomectomy-associated problem is excessive blood loss. The aim of the present study was to evaluate the effect of glypressin on blood loss during laparoscopic myomectomy (LM) in women with uterine myomas. A total of 188 women scheduled for LM for uterine myomas were divided into two groups....
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290438/ https://www.ncbi.nlm.nih.gov/pubmed/34335897 http://dx.doi.org/10.3892/etm.2021.10387 |
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author | Matasariu, Daniela Roxana Ursache, Alexandra Himiniuc, Loredana Toma, Bogdan Boiculese, Vasile Lucian Rudisteanu, Dorina Dumitrascu, Irina |
author_facet | Matasariu, Daniela Roxana Ursache, Alexandra Himiniuc, Loredana Toma, Bogdan Boiculese, Vasile Lucian Rudisteanu, Dorina Dumitrascu, Irina |
author_sort | Matasariu, Daniela Roxana |
collection | PubMed |
description | A major myomectomy-associated problem is excessive blood loss. The aim of the present study was to evaluate the effect of glypressin on blood loss during laparoscopic myomectomy (LM) in women with uterine myomas. A total of 188 women scheduled for LM for uterine myomas were divided into two groups. The one group of women (n=64) received a 5-ml intramyometrial injection of glypressin 0.2 mg/ml (glypressin group; group 1). The other group of women (n=124) (group 2) had an LM performed without any other method to reduce blood loss. The decrease in postoperative hemoglobin (Hb), hematocrit (Ht), morbidity and duration of hospital stay were assessed. The results revealed that Hb and Ht (as it was presumed) exhibited similar changes in our study. Statistically significant differences (P<0.05) were obtained between the two groups in terms of Hb and Ht; after LM both Hb and Ht were decreased. In conclusion, the impact of glypressin administration in hemorrhage control in uterine leiomyomas may establish new future perspectives, regarding its administration in gynecological hemorrhagic pathologies. |
format | Online Article Text |
id | pubmed-8290438 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-82904382021-07-30 A Romanian study on the impact of glypressin in laparoscopic myomectomy Matasariu, Daniela Roxana Ursache, Alexandra Himiniuc, Loredana Toma, Bogdan Boiculese, Vasile Lucian Rudisteanu, Dorina Dumitrascu, Irina Exp Ther Med Articles A major myomectomy-associated problem is excessive blood loss. The aim of the present study was to evaluate the effect of glypressin on blood loss during laparoscopic myomectomy (LM) in women with uterine myomas. A total of 188 women scheduled for LM for uterine myomas were divided into two groups. The one group of women (n=64) received a 5-ml intramyometrial injection of glypressin 0.2 mg/ml (glypressin group; group 1). The other group of women (n=124) (group 2) had an LM performed without any other method to reduce blood loss. The decrease in postoperative hemoglobin (Hb), hematocrit (Ht), morbidity and duration of hospital stay were assessed. The results revealed that Hb and Ht (as it was presumed) exhibited similar changes in our study. Statistically significant differences (P<0.05) were obtained between the two groups in terms of Hb and Ht; after LM both Hb and Ht were decreased. In conclusion, the impact of glypressin administration in hemorrhage control in uterine leiomyomas may establish new future perspectives, regarding its administration in gynecological hemorrhagic pathologies. D.A. Spandidos 2021-09 2021-07-06 /pmc/articles/PMC8290438/ /pubmed/34335897 http://dx.doi.org/10.3892/etm.2021.10387 Text en Copyright: © Matasariu et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Articles Matasariu, Daniela Roxana Ursache, Alexandra Himiniuc, Loredana Toma, Bogdan Boiculese, Vasile Lucian Rudisteanu, Dorina Dumitrascu, Irina A Romanian study on the impact of glypressin in laparoscopic myomectomy |
title | A Romanian study on the impact of glypressin in laparoscopic myomectomy |
title_full | A Romanian study on the impact of glypressin in laparoscopic myomectomy |
title_fullStr | A Romanian study on the impact of glypressin in laparoscopic myomectomy |
title_full_unstemmed | A Romanian study on the impact of glypressin in laparoscopic myomectomy |
title_short | A Romanian study on the impact of glypressin in laparoscopic myomectomy |
title_sort | romanian study on the impact of glypressin in laparoscopic myomectomy |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290438/ https://www.ncbi.nlm.nih.gov/pubmed/34335897 http://dx.doi.org/10.3892/etm.2021.10387 |
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