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Microglial responses to CSF1 overexpression do not promote the expansion of other glial lineages

BACKGROUND: Colony-stimulating factor 1 (CSF1) expression in the central nervous system (CNS) increases in response to a variety of stimuli, and CSF1 is overexpressed in many CNS diseases. In young adult mice, we previously showed that CSF1 overexpression in the CNS caused the proliferation of IBA1(...

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Detalles Bibliográficos
Autores principales: De, Ishani, Maklakova, Vilena, Litscher, Suzanne, Boyd, Michelle M., Klemm, Lucas C., Wang, Ziyue, Kendziorski, Christina, Collier, Lara S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290555/
https://www.ncbi.nlm.nih.gov/pubmed/34281564
http://dx.doi.org/10.1186/s12974-021-02212-0