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Microglial responses to CSF1 overexpression do not promote the expansion of other glial lineages
BACKGROUND: Colony-stimulating factor 1 (CSF1) expression in the central nervous system (CNS) increases in response to a variety of stimuli, and CSF1 is overexpressed in many CNS diseases. In young adult mice, we previously showed that CSF1 overexpression in the CNS caused the proliferation of IBA1(...
Autores principales: | De, Ishani, Maklakova, Vilena, Litscher, Suzanne, Boyd, Michelle M., Klemm, Lucas C., Wang, Ziyue, Kendziorski, Christina, Collier, Lara S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290555/ https://www.ncbi.nlm.nih.gov/pubmed/34281564 http://dx.doi.org/10.1186/s12974-021-02212-0 |
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