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Oxidative stress tolerance contributes to heterologous protein production in Pichia pastoris

BACKGROUND: Pichia pastoris (syn. Komagataella phaffii) is an important yeast system for heterologous protein expression. A robust P. pastoris mutant with oxidative and thermal stress cross-tolerance was acquired in our previous study. The robust mutant can express a 2.5-fold higher level of lipase...

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Detalles Bibliográficos
Autores principales: Lin, Nai-Xin, He, Rui-Zhen, Xu, Yan, Yu, Xiao-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290557/
https://www.ncbi.nlm.nih.gov/pubmed/34284814
http://dx.doi.org/10.1186/s13068-021-02013-w