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Genetic pathogenesis of immunoglobulin light chain amyloidosis: basic characteristics and clinical applications

Immunoglobulin light chain amyloidosis (AL) is an indolent plasma cell disorder characterized by free immunoglobulin light chain (FLC) misfolding and amyloid fibril deposition. The cytogenetic pattern of AL shows profound similarity with that of other plasma cell disorders but harbors distinct featu...

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Detalles Bibliográficos
Autores principales: Xu, Linchun, Su, Yongzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290569/
https://www.ncbi.nlm.nih.gov/pubmed/34284823
http://dx.doi.org/10.1186/s40164-021-00236-z