Cargando…

Selective Neuron Vulnerability in Common and Rare Diseases—Mitochondria in the Focus

Mitochondrial dysfunction is a central feature of neurodegeneration within the central and peripheral nervous system, highlighting a strong dependence on proper mitochondrial function of neurons with especially high energy consumptions. The fitness of mitochondria critically depends on preservation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Paß, Thomas, Wiesner, Rudolf J., Pla-Martín, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290884/ https://www.ncbi.nlm.nih.gov/pubmed/34295920 http://dx.doi.org/10.3389/fmolb.2021.676187

Ejemplares similares

Extraocular Muscle Reveals Selective Vulnerability of Type IIB Fibers to Respiratory Chain Defects Induced by Mitochondrial DNA Alterations
por: Oexner, Rafael R., et al.
Publicado: (2020)

Focus on the Role of D-serine and D-amino Acid Oxidase in Amyotrophic Lateral Sclerosis/Motor Neuron Disease (ALS)
por: Kondori, Nazanin R., et al.
Publicado: (2018)

Mitochondria-Associated Membrane Scaffolding with Endoplasmic Reticulum: A Dynamic Pathway of Developmental Disease
por: Saneto, Russell P., et al.
Publicado: (2022)

NADH Fluorescence Lifetime Imaging Microscopy Reveals Selective Mitochondrial Dysfunction in Neurons Overexpressing Alzheimer’s Disease–Related Proteins
por: Niederschweiberer, Moritz A., et al.
Publicado: (2021)

Protein Translocation into the Intermembrane Space and Matrix of Mitochondria: Mechanisms and Driving Forces
por: Backes, Sandra, et al.
Publicado: (2017)

Characterization of a Novel Mitochondrial Ascorbate Transporter From Rat Liver and Potato Mitochondria
por: Scalera, Vito, et al.
Publicado: (2018)

Understanding the Holobiont: Crosstalk Between Gut Microbiota and Mitochondria During Long Exercise in Horse
por: Mach, Núria, et al.
Publicado: (2021)

The intriguing dose-dependent effect of selected amphiphilic compounds on insulin amyloid aggregation: Focus on a cholesterol-based detergent, Chobimalt
por: Siposova, Katarina, et al.
Publicado: (2022)

The Brazilian Rare Genomes Project: Validation of Whole Genome Sequencing for Rare Diseases Diagnosis
por: Coelho, Antonio Victor Campos, et al.
Publicado: (2022)

Resources and tools for rare disease variant interpretation
por: Licata, Luana, et al.
Publicado: (2023)

Role of mitochondria-associated endoplasmic reticulum membranes in insulin sensitivity, energy metabolism, and contraction of skeletal muscle
por: Nieblas, Bianca, et al.
Publicado: (2022)

Network Simulations Reveal Molecular Signatures of Vulnerability to Age-Dependent Stress and Tau Accumulation
por: Hoffman, Timothy E., et al.
Publicado: (2020)

Impact of Alcohol Abuse on Susceptibility to Rare Neurodegenerative Diseases
por: Araujo, Iskra, et al.
Publicado: (2021)

Editorial: A focus on chaperone clients
por: Horovitz, Amnon, et al.
Publicado: (2023)

Emerging therapies for autosomal dominant polycystic kidney disease with a focus on cAMP signaling
por: Zhou, Xia, et al.
Publicado: (2022)

Artificial Intelligence in Epigenetic Studies: Shedding Light on Rare Diseases
por: Brasil, Sandra, et al.
Publicado: (2021)

A synthetic lethal screen for Snail-induced enzalutamide resistance identifies JAK/STAT signaling as a therapeutic vulnerability in prostate cancer
por: Ware, Kathryn E., et al.
Publicado: (2023)

Editorial: AI and Multi-Omics for Rare Diseases: Challenges, Advances and Perspectives
por: Bottini, Silvia, et al.
Publicado: (2021)

Commentary: Synthetic Ubiquinones Specifically Bind to Mitochondrial Voltage-Dependent Anion Channel 1 (VDAC1) in Saccharomyces cerevisiae Mitochondria
por: Gutiérrez-Aguilar, Manuel
Publicado: (2017)

In Vivo Pravastatin Treatment Reverses Hypercholesterolemia Induced Mitochondria-Associated Membranes Contact Sites, Foam Cell Formation, and Phagocytosis in Macrophages
por: Assis, Leandro Henrique de Paula, et al.
Publicado: (2022)

Focusing on Mechanoregulation Axis in Fibrosis: Sensing, Transduction and Effecting
por: Wen, Dongsheng, et al.
Publicado: (2022)

Rare phylotypes in stone, stool, and urine microbiomes are associated with urinary stone disease
por: Suryavanshi, Mangesh, et al.
Publicado: (2023)

Redox Switches in Noise-Induced Cardiovascular and Neuronal Dysregulation
por: Frenis, Katie, et al.
Publicado: (2021)

RNA-Binding Protein MSI2 Binds to miR-301a-3p and Facilitates Its Distribution in Mitochondria of Endothelial Cells
por: Guo, Qian Qian, et al.
Publicado: (2021)

Regulation of DNA Double Strand Breaks Processing: Focus on Barriers
por: Marini, Federica, et al.
Publicado: (2019)

Corrigendum: Focusing on Mechanoregulation Axis in Fibrosis: Sensing, Transduction and Effecting
por: Wen, Dongsheng, et al.
Publicado: (2022)

Editorial: AI and multi-omics for rare diseases: Challenges, advances and perspectives, Volume II
por: Bottini, Silvia, et al.
Publicado: (2022)

DNAJB6 Myopathies: Focused Review on an Emerging and Expanding Group of Myopathies
por: Ruggieri, Alessandra, et al.
Publicado: (2016)

Editorial: The role of cofactors in protein stability and homeostasis: Focus on human metabolism
por: Marchetti, Marialaura, et al.
Publicado: (2023)

Neuronal ferroptosis after intracerebral hemorrhage
por: Ren, Siying, et al.
Publicado: (2022)

Regulation of the proteostasis network by the neuronal system
por: Zhu, Huadong, et al.
Publicado: (2023)

Copy Number Variations in the Survival Motor Neuron Genes: Implications for Spinal Muscular Atrophy and Other Neurodegenerative Diseases
por: Butchbach, Matthew E. R.
Publicado: (2016)

Significant Quantitative Differences in Orexin Neuronal Activation After Pain Assessments in an Animal Model of Sickle Cell Disease
por: Richardson, Kimberlei, et al.
Publicado: (2020)

Post-transcriptional Regulation of Colorectal Cancer: A Focus on RNA-Binding Proteins
por: García-Cárdenas, Jennyfer M., et al.
Publicado: (2019)

Pore Forming Protein Induced Biomembrane Reorganization and Dynamics: A Focused Review
por: Ilangumaran Ponmalar, Ilanila, et al.
Publicado: (2021)

GNG5 Controls the Number of Apical and Basal Progenitors and Alters Neuronal Migration During Cortical Development
por: Ayo-Martin, Ane Cristina, et al.
Publicado: (2020)

Elevated LDL-C, high blood pressure, and low peak [Formula: see text] O(2) associate with platelet mitochondria function in children—The Arkansas Active Kids Study
por: Diaz, Eva C., et al.
Publicado: (2023)

Proteome of the Triatomine Digestive Tract: From Catalytic to Immune Pathways; Focusing on Annexin Expression
por: Gumiel, Marcia, et al.
Publicado: (2020)

Immune Crosstalk Between Lymph Nodes and Breast Carcinomas, With a Focus on B Cells
por: Alberts, Elena, et al.
Publicado: (2021)

MK-STYX Alters the Morphology of Primary Neurons, and Outgrowths in MK-STYX Overexpressing PC-12 Cells Develop a Neuronal Phenotype
por: Banks, Dallas A., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_pao8vdljp5hkjak8adfgqjjemd