Cargando…
METTL3 Promotes Activation and Inflammation of FLSs Through the NF-κB Signaling Pathway in Rheumatoid Arthritis
Rheumatoid arthritis (RA), a common autoimmune disease, is extremely damaging to human health. Fibroblast-like synoviocytes (FLSs) have a vital role in the occurrence and development of RA. Methyltransferase-like 3 (METTL3), which is a crucial component of the N(6)-methyladenosine (m(6)A) methyltran...
Autores principales: | Shi, Wen, Zheng, Yan, Luo, Shuai, Li, Xiaofeng, Zhang, Yilong, Meng, Xiaoming, Huang, Cheng, Li, Jun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290917/ https://www.ncbi.nlm.nih.gov/pubmed/34295905 http://dx.doi.org/10.3389/fmed.2021.607585 |
Ejemplares similares
-
Metformin, an AMPK Activator, Inhibits Activation of FLSs but Promotes HAPLN1 Secretion
por: Chen, Yong, et al.
Publicado: (2020) -
MicroRNA-140-5p regulates the proliferation, apoptosis and inflammation of RA FLSs by repressing STAT3
por: Zhu, Jiehua, et al.
Publicado: (2021) -
Ginkgolic acid promotes inflammation and macrophage apoptosis via SUMOylation and NF-κB pathways in sepsis
por: Liu, Xinyong, et al.
Publicado: (2023) -
IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes: JAKinibs suppress the interferon response in RA-FLSs
por: Bonelli, Michael, et al.
Publicado: (2019) -
Influences of the lncRNA TUG1‐miRNA‐34a‐5p network on fibroblast‐like synoviocytes (FLSs) dysfunction in rheumatoid arthritis through targeting the lactate dehydrogenase A (LDHA)
por: Zhang, Mei, et al.
Publicado: (2021)