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Polymorphisms in TYMS for Prediction of Capecitabine-Induced Hand-Foot Syndrome in Chinese Patients with Colorectal Cancer

PURPOSE: Capecitabine is an extensively used oral prodrug of 5-fluorouracil in treatment of colon cancer and is known to cause hand-foot syndrome (HFS). As the target enzyme for capecitabine, thymidylate synthase (TYMS) plays a key role for 5-fluorouracil metabolism and has been associated with some...

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Detalles Bibliográficos
Autores principales:	Dong, Si-Qi, Wang, Tong-Min, Zhang, Jiang-Bo, He, Yong-Qiao, Xue, Wen-Qiong, Wu, Zi-Yi, Yang, Da-Wei, Cao, Lian-Jing, Huang, Jing-Wen, Li, Xi-Zhao, Zhang, Pei-Fen, Zheng, Xiao-Hui, Jia, Wei-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Cancer Association 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291172/ https://www.ncbi.nlm.nih.gov/pubmed/33285053 http://dx.doi.org/10.4143/crt.2020.457

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