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Visually constructing the chemical structure of a single molecule by scanning Raman picoscopy
The strong spatial confinement of a nanocavity plasmonic field has made it possible to visualize the inner structure of a single molecule and even to distinguish its vibrational modes in real space. With such ever-improved spatial resolution, it is anticipated that full vibrational imaging of a mole...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291412/ https://www.ncbi.nlm.nih.gov/pubmed/34691995 http://dx.doi.org/10.1093/nsr/nwz180 |
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author | Zhang, Yao Yang, Ben Ghafoor, Atif Zhang, Yang Zhang, Yu-Fan Wang, Rui-Pu Yang, Jin-Long Luo, Yi Dong, Zhen-Chao Hou, J G |
author_facet | Zhang, Yao Yang, Ben Ghafoor, Atif Zhang, Yang Zhang, Yu-Fan Wang, Rui-Pu Yang, Jin-Long Luo, Yi Dong, Zhen-Chao Hou, J G |
author_sort | Zhang, Yao |
collection | PubMed |
description | The strong spatial confinement of a nanocavity plasmonic field has made it possible to visualize the inner structure of a single molecule and even to distinguish its vibrational modes in real space. With such ever-improved spatial resolution, it is anticipated that full vibrational imaging of a molecule could be achieved to reveal molecular structural details. Here we demonstrate full Raman images of individual vibrational modes at the ångström level for a single Mg-porphine molecule, revealing distinct characteristics of each vibrational mode in real space. Furthermore, by exploiting the underlying interference effect and Raman fingerprint database, we propose a new methodology for structural determination, which we have called ‘scanning Raman picoscopy’, to show how such ultrahigh-resolution spectromicroscopic vibrational images can be used to visually assemble the chemical structure of a single molecule through a simple Lego-like building process. |
format | Online Article Text |
id | pubmed-8291412 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-82914122021-10-21 Visually constructing the chemical structure of a single molecule by scanning Raman picoscopy Zhang, Yao Yang, Ben Ghafoor, Atif Zhang, Yang Zhang, Yu-Fan Wang, Rui-Pu Yang, Jin-Long Luo, Yi Dong, Zhen-Chao Hou, J G Natl Sci Rev Research Article The strong spatial confinement of a nanocavity plasmonic field has made it possible to visualize the inner structure of a single molecule and even to distinguish its vibrational modes in real space. With such ever-improved spatial resolution, it is anticipated that full vibrational imaging of a molecule could be achieved to reveal molecular structural details. Here we demonstrate full Raman images of individual vibrational modes at the ångström level for a single Mg-porphine molecule, revealing distinct characteristics of each vibrational mode in real space. Furthermore, by exploiting the underlying interference effect and Raman fingerprint database, we propose a new methodology for structural determination, which we have called ‘scanning Raman picoscopy’, to show how such ultrahigh-resolution spectromicroscopic vibrational images can be used to visually assemble the chemical structure of a single molecule through a simple Lego-like building process. Oxford University Press 2019-11 2019-11-08 /pmc/articles/PMC8291412/ /pubmed/34691995 http://dx.doi.org/10.1093/nsr/nwz180 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of China Science Publishing & Media Ltd. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Zhang, Yao Yang, Ben Ghafoor, Atif Zhang, Yang Zhang, Yu-Fan Wang, Rui-Pu Yang, Jin-Long Luo, Yi Dong, Zhen-Chao Hou, J G Visually constructing the chemical structure of a single molecule by scanning Raman picoscopy |
title | Visually constructing the chemical structure of a single molecule by scanning Raman picoscopy |
title_full | Visually constructing the chemical structure of a single molecule by scanning Raman picoscopy |
title_fullStr | Visually constructing the chemical structure of a single molecule by scanning Raman picoscopy |
title_full_unstemmed | Visually constructing the chemical structure of a single molecule by scanning Raman picoscopy |
title_short | Visually constructing the chemical structure of a single molecule by scanning Raman picoscopy |
title_sort | visually constructing the chemical structure of a single molecule by scanning raman picoscopy |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291412/ https://www.ncbi.nlm.nih.gov/pubmed/34691995 http://dx.doi.org/10.1093/nsr/nwz180 |
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