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Visually constructing the chemical structure of a single molecule by scanning Raman picoscopy

The strong spatial confinement of a nanocavity plasmonic field has made it possible to visualize the inner structure of a single molecule and even to distinguish its vibrational modes in real space. With such ever-improved spatial resolution, it is anticipated that full vibrational imaging of a mole...

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Autores principales: Zhang, Yao, Yang, Ben, Ghafoor, Atif, Zhang, Yang, Zhang, Yu-Fan, Wang, Rui-Pu, Yang, Jin-Long, Luo, Yi, Dong, Zhen-Chao, Hou, J G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291412/
https://www.ncbi.nlm.nih.gov/pubmed/34691995
http://dx.doi.org/10.1093/nsr/nwz180
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author Zhang, Yao
Yang, Ben
Ghafoor, Atif
Zhang, Yang
Zhang, Yu-Fan
Wang, Rui-Pu
Yang, Jin-Long
Luo, Yi
Dong, Zhen-Chao
Hou, J G
author_facet Zhang, Yao
Yang, Ben
Ghafoor, Atif
Zhang, Yang
Zhang, Yu-Fan
Wang, Rui-Pu
Yang, Jin-Long
Luo, Yi
Dong, Zhen-Chao
Hou, J G
author_sort Zhang, Yao
collection PubMed
description The strong spatial confinement of a nanocavity plasmonic field has made it possible to visualize the inner structure of a single molecule and even to distinguish its vibrational modes in real space. With such ever-improved spatial resolution, it is anticipated that full vibrational imaging of a molecule could be achieved to reveal molecular structural details. Here we demonstrate full Raman images of individual vibrational modes at the ångström level for a single Mg-porphine molecule, revealing distinct characteristics of each vibrational mode in real space. Furthermore, by exploiting the underlying interference effect and Raman fingerprint database, we propose a new methodology for structural determination, which we have called ‘scanning Raman picoscopy’, to show how such ultrahigh-resolution spectromicroscopic vibrational images can be used to visually assemble the chemical structure of a single molecule through a simple Lego-like building process.
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spelling pubmed-82914122021-10-21 Visually constructing the chemical structure of a single molecule by scanning Raman picoscopy Zhang, Yao Yang, Ben Ghafoor, Atif Zhang, Yang Zhang, Yu-Fan Wang, Rui-Pu Yang, Jin-Long Luo, Yi Dong, Zhen-Chao Hou, J G Natl Sci Rev Research Article The strong spatial confinement of a nanocavity plasmonic field has made it possible to visualize the inner structure of a single molecule and even to distinguish its vibrational modes in real space. With such ever-improved spatial resolution, it is anticipated that full vibrational imaging of a molecule could be achieved to reveal molecular structural details. Here we demonstrate full Raman images of individual vibrational modes at the ångström level for a single Mg-porphine molecule, revealing distinct characteristics of each vibrational mode in real space. Furthermore, by exploiting the underlying interference effect and Raman fingerprint database, we propose a new methodology for structural determination, which we have called ‘scanning Raman picoscopy’, to show how such ultrahigh-resolution spectromicroscopic vibrational images can be used to visually assemble the chemical structure of a single molecule through a simple Lego-like building process. Oxford University Press 2019-11 2019-11-08 /pmc/articles/PMC8291412/ /pubmed/34691995 http://dx.doi.org/10.1093/nsr/nwz180 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of China Science Publishing & Media Ltd. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zhang, Yao
Yang, Ben
Ghafoor, Atif
Zhang, Yang
Zhang, Yu-Fan
Wang, Rui-Pu
Yang, Jin-Long
Luo, Yi
Dong, Zhen-Chao
Hou, J G
Visually constructing the chemical structure of a single molecule by scanning Raman picoscopy
title Visually constructing the chemical structure of a single molecule by scanning Raman picoscopy
title_full Visually constructing the chemical structure of a single molecule by scanning Raman picoscopy
title_fullStr Visually constructing the chemical structure of a single molecule by scanning Raman picoscopy
title_full_unstemmed Visually constructing the chemical structure of a single molecule by scanning Raman picoscopy
title_short Visually constructing the chemical structure of a single molecule by scanning Raman picoscopy
title_sort visually constructing the chemical structure of a single molecule by scanning raman picoscopy
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291412/
https://www.ncbi.nlm.nih.gov/pubmed/34691995
http://dx.doi.org/10.1093/nsr/nwz180
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