Transgenic rhesus monkeys carrying the human MCPH1 gene copies show human-like neoteny of brain development

Brain size and cognitive skills are the most dramatically changed traits in humans during evolution and yet the genetic mechanisms underlying these human-specific changes remain elusive. Here, we successfully generated 11 transgenic rhesus monkeys (8 first-generation and 3 second-generation) carryin...

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Detalles Bibliográficos
Autores principales: Shi, Lei, Luo, Xin, Jiang, Jin, Chen, Yongchang, Liu, Cirong, Hu, Ting, Li, Min, Lin, Qiang, Li, Yanjiao, Huang, Jun, Wang, Hong, Niu, Yuyu, Shi, Yundi, Styner, Martin, Wang, Jianhong, Lu, Yi, Sun, Xuejin, Yu, Hualin, Ji, Weizhi, Su, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291473/
https://www.ncbi.nlm.nih.gov/pubmed/34691896
http://dx.doi.org/10.1093/nsr/nwz043

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