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Predictors of Late Presentation for HIV/AIDS in West Arsi Zone Public Health Institutions, South Ethiopia: Unmatched Case–Control Study

BACKGROUND: Late presentation for HIV/AIDS care is defined as individuals newly presenting for HIV/AIDS care with a CD4 count below 350 cells/μl or presenting for care with WHO clinical staging of stage III or IV. Globally, around 21.7 million people living with HIV/AIDS were receiving ART in 2017,...

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Autores principales: Degno, Sisay, Atlaw, Daniel, Mekonnen, Ashenafi, Lencha, Bikila, Kumsa, Kebede, Tekalegn, Yohannes, Walle, Gashaw, Niggussie, Ashebir, Aman, Rameto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291576/
https://www.ncbi.nlm.nih.gov/pubmed/34295191
http://dx.doi.org/10.2147/HIV.S313139
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author Degno, Sisay
Atlaw, Daniel
Mekonnen, Ashenafi
Lencha, Bikila
Kumsa, Kebede
Tekalegn, Yohannes
Walle, Gashaw
Niggussie, Ashebir
Aman, Rameto
author_facet Degno, Sisay
Atlaw, Daniel
Mekonnen, Ashenafi
Lencha, Bikila
Kumsa, Kebede
Tekalegn, Yohannes
Walle, Gashaw
Niggussie, Ashebir
Aman, Rameto
author_sort Degno, Sisay
collection PubMed
description BACKGROUND: Late presentation for HIV/AIDS care is defined as individuals newly presenting for HIV/AIDS care with a CD4 count below 350 cells/μl or presenting for care with WHO clinical staging of stage III or IV. Globally, around 21.7 million people living with HIV/AIDS were receiving ART in 2017, with an increase of 2.3 million since 2016. Despite this progress, most people start ART late in their disease progression. OBJECTIVE: This study aims to identify predictors of late presentation for HIV/AIDS among people living with HIV and attending ART clinics in West Arsi Zone public health institutions, South Ethiopia, 2019. METHODOLOGY: A facility-based unmatched case–control study was conducted among people living with HIV attending ART clinics in West Arsi Zone public health institutions, with a total sample size of 500 (167 cases and 333 controls). The sample size was calculated using Epi info version 7 and participants were selected using the case-based control selection sampling technique. Descriptive statistics were carried out to summarize the data. Bi-variate binary logistic regression analysis was carried for selecting candidate variables for multivariate binary logistic regression. A p-value of <0.05 was taken to declare the presence of a statistical association between outcomes and explanatory variables. RESULTS: Rural residence (AOR=7.74 95% CI (3.4–17.6)), being single (AOR=0.18 95% CI (0.06–0.49)) symptom(s) at first HIV diagnosis (AOR=7.69 95% CI (4.09–14.4)), no private house (AOR=5.09 95% CI (2.47–10.45)), fear of losing job (AOR=4.12 95% CI (2.04–8.31)), alcohol consumption (AOR=4.35 95% CI (2.18–8.69), and having chronic medical illness (AOR=5.04 95% CI (2.48–10.24)) were identified as having significant associations with late presentation of HIV/AIDS care. CONCLUSION: Rural residence, fear of losing a job, and chronic medical illness were potential risk factors for late presentation of HIV/AIDS care. Being single is the only protective factor for the late presentation of HIV/AIDS care.
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spelling pubmed-82915762021-07-21 Predictors of Late Presentation for HIV/AIDS in West Arsi Zone Public Health Institutions, South Ethiopia: Unmatched Case–Control Study Degno, Sisay Atlaw, Daniel Mekonnen, Ashenafi Lencha, Bikila Kumsa, Kebede Tekalegn, Yohannes Walle, Gashaw Niggussie, Ashebir Aman, Rameto HIV AIDS (Auckl) Original Research BACKGROUND: Late presentation for HIV/AIDS care is defined as individuals newly presenting for HIV/AIDS care with a CD4 count below 350 cells/μl or presenting for care with WHO clinical staging of stage III or IV. Globally, around 21.7 million people living with HIV/AIDS were receiving ART in 2017, with an increase of 2.3 million since 2016. Despite this progress, most people start ART late in their disease progression. OBJECTIVE: This study aims to identify predictors of late presentation for HIV/AIDS among people living with HIV and attending ART clinics in West Arsi Zone public health institutions, South Ethiopia, 2019. METHODOLOGY: A facility-based unmatched case–control study was conducted among people living with HIV attending ART clinics in West Arsi Zone public health institutions, with a total sample size of 500 (167 cases and 333 controls). The sample size was calculated using Epi info version 7 and participants were selected using the case-based control selection sampling technique. Descriptive statistics were carried out to summarize the data. Bi-variate binary logistic regression analysis was carried for selecting candidate variables for multivariate binary logistic regression. A p-value of <0.05 was taken to declare the presence of a statistical association between outcomes and explanatory variables. RESULTS: Rural residence (AOR=7.74 95% CI (3.4–17.6)), being single (AOR=0.18 95% CI (0.06–0.49)) symptom(s) at first HIV diagnosis (AOR=7.69 95% CI (4.09–14.4)), no private house (AOR=5.09 95% CI (2.47–10.45)), fear of losing job (AOR=4.12 95% CI (2.04–8.31)), alcohol consumption (AOR=4.35 95% CI (2.18–8.69), and having chronic medical illness (AOR=5.04 95% CI (2.48–10.24)) were identified as having significant associations with late presentation of HIV/AIDS care. CONCLUSION: Rural residence, fear of losing a job, and chronic medical illness were potential risk factors for late presentation of HIV/AIDS care. Being single is the only protective factor for the late presentation of HIV/AIDS care. Dove 2021-07-13 /pmc/articles/PMC8291576/ /pubmed/34295191 http://dx.doi.org/10.2147/HIV.S313139 Text en © 2021 Degno et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Degno, Sisay
Atlaw, Daniel
Mekonnen, Ashenafi
Lencha, Bikila
Kumsa, Kebede
Tekalegn, Yohannes
Walle, Gashaw
Niggussie, Ashebir
Aman, Rameto
Predictors of Late Presentation for HIV/AIDS in West Arsi Zone Public Health Institutions, South Ethiopia: Unmatched Case–Control Study
title Predictors of Late Presentation for HIV/AIDS in West Arsi Zone Public Health Institutions, South Ethiopia: Unmatched Case–Control Study
title_full Predictors of Late Presentation for HIV/AIDS in West Arsi Zone Public Health Institutions, South Ethiopia: Unmatched Case–Control Study
title_fullStr Predictors of Late Presentation for HIV/AIDS in West Arsi Zone Public Health Institutions, South Ethiopia: Unmatched Case–Control Study
title_full_unstemmed Predictors of Late Presentation for HIV/AIDS in West Arsi Zone Public Health Institutions, South Ethiopia: Unmatched Case–Control Study
title_short Predictors of Late Presentation for HIV/AIDS in West Arsi Zone Public Health Institutions, South Ethiopia: Unmatched Case–Control Study
title_sort predictors of late presentation for hiv/aids in west arsi zone public health institutions, south ethiopia: unmatched case–control study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291576/
https://www.ncbi.nlm.nih.gov/pubmed/34295191
http://dx.doi.org/10.2147/HIV.S313139
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