Integrase Strand Transfer Inhibitors and Weight Gain in Children and Youth With Perinatal Human Immunodeficiency Virus in the DC Cohort

We conducted a retrospective analysis of 38 children and youth with human immunodeficiency virus (aged 0–19 years) in the United States and report an increased rate of change of BMI-for-age z score after initiating integrase strand transfer inhibitors (+0.19 z score units/year [95% confidence interv...

Descripción completa

Detalles Bibliográficos
Autores principales: Koay, Wei Li A, Dirajlal-Fargo, Sahera, Levy, Matthew E, Kulie, Paige, Monroe, Anne, Castel, Amanda D, Rakhmanina, Natella Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291625/
https://www.ncbi.nlm.nih.gov/pubmed/34295943
http://dx.doi.org/10.1093/ofid/ofab308
_version_ 1783724676658233344
author Koay, Wei Li A
Dirajlal-Fargo, Sahera
Levy, Matthew E
Kulie, Paige
Monroe, Anne
Castel, Amanda D
Rakhmanina, Natella Y
author_facet Koay, Wei Li A
Dirajlal-Fargo, Sahera
Levy, Matthew E
Kulie, Paige
Monroe, Anne
Castel, Amanda D
Rakhmanina, Natella Y
author_sort Koay, Wei Li A
collection PubMed
description We conducted a retrospective analysis of 38 children and youth with human immunodeficiency virus (aged 0–19 years) in the United States and report an increased rate of change of BMI-for-age z score after initiating integrase strand transfer inhibitors (+0.19 z score units/year [95% confidence interval, .01–.37]; P = .036) for a median follow-up of 527.5 days.
format Online
Article
Text
id pubmed-8291625
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-82916252021-07-21 Integrase Strand Transfer Inhibitors and Weight Gain in Children and Youth With Perinatal Human Immunodeficiency Virus in the DC Cohort Koay, Wei Li A Dirajlal-Fargo, Sahera Levy, Matthew E Kulie, Paige Monroe, Anne Castel, Amanda D Rakhmanina, Natella Y Open Forum Infect Dis Brief Reports We conducted a retrospective analysis of 38 children and youth with human immunodeficiency virus (aged 0–19 years) in the United States and report an increased rate of change of BMI-for-age z score after initiating integrase strand transfer inhibitors (+0.19 z score units/year [95% confidence interval, .01–.37]; P = .036) for a median follow-up of 527.5 days. Oxford University Press 2021-07-01 /pmc/articles/PMC8291625/ /pubmed/34295943 http://dx.doi.org/10.1093/ofid/ofab308 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Koay, Wei Li A
Dirajlal-Fargo, Sahera
Levy, Matthew E
Kulie, Paige
Monroe, Anne
Castel, Amanda D
Rakhmanina, Natella Y
Integrase Strand Transfer Inhibitors and Weight Gain in Children and Youth With Perinatal Human Immunodeficiency Virus in the DC Cohort
title Integrase Strand Transfer Inhibitors and Weight Gain in Children and Youth With Perinatal Human Immunodeficiency Virus in the DC Cohort
title_full Integrase Strand Transfer Inhibitors and Weight Gain in Children and Youth With Perinatal Human Immunodeficiency Virus in the DC Cohort
title_fullStr Integrase Strand Transfer Inhibitors and Weight Gain in Children and Youth With Perinatal Human Immunodeficiency Virus in the DC Cohort
title_full_unstemmed Integrase Strand Transfer Inhibitors and Weight Gain in Children and Youth With Perinatal Human Immunodeficiency Virus in the DC Cohort
title_short Integrase Strand Transfer Inhibitors and Weight Gain in Children and Youth With Perinatal Human Immunodeficiency Virus in the DC Cohort
title_sort integrase strand transfer inhibitors and weight gain in children and youth with perinatal human immunodeficiency virus in the dc cohort
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291625/
https://www.ncbi.nlm.nih.gov/pubmed/34295943
http://dx.doi.org/10.1093/ofid/ofab308
work_keys_str_mv AT koayweilia integrasestrandtransferinhibitorsandweightgaininchildrenandyouthwithperinatalhumanimmunodeficiencyvirusinthedccohort
AT dirajlalfargosahera integrasestrandtransferinhibitorsandweightgaininchildrenandyouthwithperinatalhumanimmunodeficiencyvirusinthedccohort
AT levymatthewe integrasestrandtransferinhibitorsandweightgaininchildrenandyouthwithperinatalhumanimmunodeficiencyvirusinthedccohort
AT kuliepaige integrasestrandtransferinhibitorsandweightgaininchildrenandyouthwithperinatalhumanimmunodeficiencyvirusinthedccohort
AT monroeanne integrasestrandtransferinhibitorsandweightgaininchildrenandyouthwithperinatalhumanimmunodeficiencyvirusinthedccohort
AT castelamandad integrasestrandtransferinhibitorsandweightgaininchildrenandyouthwithperinatalhumanimmunodeficiencyvirusinthedccohort
AT rakhmaninanatellay integrasestrandtransferinhibitorsandweightgaininchildrenandyouthwithperinatalhumanimmunodeficiencyvirusinthedccohort
AT integrasestrandtransferinhibitorsandweightgaininchildrenandyouthwithperinatalhumanimmunodeficiencyvirusinthedccohort

Ejemplares similares