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Impact of temporal correlations on high risk outbreaks of independent and cooperative SIR dynamics

We first propose a quantitative approach to detect high risk outbreaks of independent and coinfective SIR dynamics on three empirical networks: a school, a conference and a hospital contact network. This measurement is based on the k-means clustering method and identifies proper samples for calculat...

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Autores principales: Sajjadi, Sina, Ejtehadi, Mohammad Reza, Ghanbarnejad, Fakhteh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291698/
https://www.ncbi.nlm.nih.gov/pubmed/34283838
http://dx.doi.org/10.1371/journal.pone.0253563
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author Sajjadi, Sina
Ejtehadi, Mohammad Reza
Ghanbarnejad, Fakhteh
author_facet Sajjadi, Sina
Ejtehadi, Mohammad Reza
Ghanbarnejad, Fakhteh
author_sort Sajjadi, Sina
collection PubMed
description We first propose a quantitative approach to detect high risk outbreaks of independent and coinfective SIR dynamics on three empirical networks: a school, a conference and a hospital contact network. This measurement is based on the k-means clustering method and identifies proper samples for calculating the mean outbreak size and the outbreak probability. Then we systematically study the impact of different temporal correlations on high risk outbreaks over the original and differently shuffled counterparts of each network. We observe that, on the one hand, in the coinfection process, randomization of the sequence of the events increases the mean outbreak size of high-risk cases. On the other hand, these correlations do not have a consistent effect on the independent infection dynamics, and can either decrease or increase this mean. Randomization of the daily pattern correlations has no strong impact on the size of the outbreak in either the coinfection or the independent spreading cases. We also observe that an increase in the mean outbreak size does not always coincide with an increase in the outbreak probability; therefore, we argue that merely considering the mean outbreak size of all realizations may lead us into falsely estimating the outbreak risks. Our results suggest that some sort of contact randomization in the organizational level in schools, events or hospitals might help to suppress the spreading dynamics while the risk of an outbreak is high.
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spelling pubmed-82916982021-07-31 Impact of temporal correlations on high risk outbreaks of independent and cooperative SIR dynamics Sajjadi, Sina Ejtehadi, Mohammad Reza Ghanbarnejad, Fakhteh PLoS One Research Article We first propose a quantitative approach to detect high risk outbreaks of independent and coinfective SIR dynamics on three empirical networks: a school, a conference and a hospital contact network. This measurement is based on the k-means clustering method and identifies proper samples for calculating the mean outbreak size and the outbreak probability. Then we systematically study the impact of different temporal correlations on high risk outbreaks over the original and differently shuffled counterparts of each network. We observe that, on the one hand, in the coinfection process, randomization of the sequence of the events increases the mean outbreak size of high-risk cases. On the other hand, these correlations do not have a consistent effect on the independent infection dynamics, and can either decrease or increase this mean. Randomization of the daily pattern correlations has no strong impact on the size of the outbreak in either the coinfection or the independent spreading cases. We also observe that an increase in the mean outbreak size does not always coincide with an increase in the outbreak probability; therefore, we argue that merely considering the mean outbreak size of all realizations may lead us into falsely estimating the outbreak risks. Our results suggest that some sort of contact randomization in the organizational level in schools, events or hospitals might help to suppress the spreading dynamics while the risk of an outbreak is high. Public Library of Science 2021-07-20 /pmc/articles/PMC8291698/ /pubmed/34283838 http://dx.doi.org/10.1371/journal.pone.0253563 Text en © 2021 Sajjadi et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Sajjadi, Sina
Ejtehadi, Mohammad Reza
Ghanbarnejad, Fakhteh
Impact of temporal correlations on high risk outbreaks of independent and cooperative SIR dynamics
title Impact of temporal correlations on high risk outbreaks of independent and cooperative SIR dynamics
title_full Impact of temporal correlations on high risk outbreaks of independent and cooperative SIR dynamics
title_fullStr Impact of temporal correlations on high risk outbreaks of independent and cooperative SIR dynamics
title_full_unstemmed Impact of temporal correlations on high risk outbreaks of independent and cooperative SIR dynamics
title_short Impact of temporal correlations on high risk outbreaks of independent and cooperative SIR dynamics
title_sort impact of temporal correlations on high risk outbreaks of independent and cooperative sir dynamics
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291698/
https://www.ncbi.nlm.nih.gov/pubmed/34283838
http://dx.doi.org/10.1371/journal.pone.0253563
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