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The interplay of SARS-CoV-2 evolution and constraints imposed by the structure and functionality of its proteins

The unprecedented pace of the sequencing of the SARS-CoV-2 virus genomes provides us with unique information about the genetic changes in a single pathogen during ongoing pandemic. By the analysis of close to 200,000 genomes we show that the patterns of the SARS-CoV-2 virus mutations along its genom...

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Detalles Bibliográficos
Autores principales: Jaroszewski, Lukasz, Iyer, Mallika, Alisoltani, Arghavan, Sedova, Mayya, Godzik, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291704/
https://www.ncbi.nlm.nih.gov/pubmed/34237054
http://dx.doi.org/10.1371/journal.pcbi.1009147