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A two-trick pony: lysosomal protease cathepsin B possesses surprising ligase activity
Cathepsin B is an important protease within the lysosome, where it helps recycle proteins to maintain proteostasis. It is also known to degrade proteins elsewhere but has no other known functionality. However, by carefully monitoring peptide digestion with liquid chromatography and mass spectrometry...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
RSC
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291735/ https://www.ncbi.nlm.nih.gov/pubmed/34291207 http://dx.doi.org/10.1039/d0cb00224k |